Now showing items 2645-2664 of 11039

    Development of Cu2ZnSnSe4 Based Thin Film Solar Cells by PVD and Chemical Based Processes 

    Neuschitzer, Markus (Date of defense: 2016-09-29)

    Nowadays mono- and multicrystalline silicon have the highest market share of all PV technologies but thin film solar cells based on CdTe or Cu(In,Ga)Se2 (CIGS) absorbers recently show promising high power conversion ...

    Development of diffuse large B-celllymphoma mouse models and role of CXCR4 in dissemination = Desarrollo de modelos murinos de linfoma difuso de células grandes B y papel de CXCR4 en diseminación 

    Moreno Jiménez, María José (Date of defense: 2014-06-10)

    Diffuse large B-cell lymphoma (DLBCL) is a clinically and genetically heterogeneous disease, accounting for 30% of all non-Hodgkin lymphoma cases. Although the addition of rituximab to standard treatment (CHOP: cyclophosphamide, ...

    Development of DNA methylation biomarkers to study epigenetic inheritance and integration of environmental stimuli 

    Sánchez Baizán, Núria (Date of defense: 2023-10-27)

    [eng] Epigenetic mechanisms play a vital role in gene expression regulation and phenotype determination. This thesis aimed to comprehensively investigate the transcriptome, the methylome and the influence of intrinsic (such ...

    Development of doubled haploids, chromosome doubling and CRISPR/Cas9 techniques in melon for the next generation of breeding 

    Hooghvorst, Isidre (Date of defense: 2021-04-28)

    The general aim of this PhD thesis was to study, develop and apply different breeding techniques in melon species in order to produce new commercial cultivars. The three specific objectives of this thesis are: 1. To ...

    Development of electrochemical platforms for DNA sensing 

    Alfonso Pardo, Wilmer (Date of defense: 2016-02-08)

    The present doctoral thesis is framed in the research and development (R & D) project between a private biotechnology company of molecular diagnostics Genomica SAU, the Institute for Bioengineering of Catalonia (IBEC), the ...

    Development of GasChromatographic/Mass Spectrometric procedures and Synchroton Radiation based techniques for the study of painting materials in works of art 

    Lluveras Tenorio, Anna (Date of defense: 2009-06-30)

    El estudio de muestras de pintura persigue diferentes objetivos. Por un lado, identificar los materiales y técnica de la pintura de una época y por lo tanto el know-how de un período histórico. Por otra parte, estudiar la ...

    Development of high-resolution L4 ocean wind products 

    Trindade, Ana Filipa Mestre (Date of defense: 2023-01-16)

    [eng] Heat, moisture, gas, and momentum exchanges at the oceanic and atmospheric interface modulate, inter alia, the Earth’s heat and carbon budgets, global circulation, and dynamical modes. Sea surface winds are fundamental ...

    Development of innovative analytical strategies for olive oil quality and authenticity assessment 

    Quintanilla Casas, Beatriz (Date of defense: 2022-04-01)

    Olive oil (OO) is a highly appreciated food product due to its nutritional value and organoleptic properties, marketed worldwide. In spite of being one of the most regulated food products, its high economic value becomes ...

    Development of light-modulated allosteric ligands for remote, non-invasive control of neuronal receptors 

    Pittolo, Silvia (Date of defense: 2016-01-29)

    In the brain events happen in the scale of milliseconds, and the fine processes of neurons and neuroglia are highly compartmentalized at a microscopic level. These exclusive features of the brain define extremely precise ...

    Development of model-driven approaches for metabolic flux analysis and anticancer drug discovery 

    Foguet Coll, Carles (Date of defense: 2019-12-20)

    Metabolism is a hallmark of life and underlies most biological processes in both health and disease. For instance, dysregulation of liver metabolism underlies multifactorial disorders such as diabetes or obesity. Similarly, ...

    Development of multifunctional polymeric nanoparticles by nano-emulsion templating as advanced nanocarriers targeting the blood-brain barrier 

    Fornaguera Puigvert, Cristina (Date of defense: 2015-01-21)

    Multifunctional polymeric nanoparticles (NP) represent a promising alternative for the treatment of neurodegenerative diseases using the intravenous route (i.v.). In current treatments, the effects of the intravenously ...

    Development of nanovectors for the targeted drug delivery of antimalarials 

    Urbán, Patricia (Date of defense: 2013-02-11)

    Malaria is arguably one of the main medical concerns worldwide because of the numbers of people affected, the severity of the disease, and the complexity of the life cycle of its causative agent, the protozoan Plasmodium ...

    Development of new antimicrobial peptides and peptidomimetics and mechanism of resistance to peptide antibiotics 

    Vila Farrés, Xavier (Date of defense: 2014-11-14)

    Nowadays in the world there is a very big problem associated with two factors related to each other. The first factor is the increase in the resistant of certain bacteria, especially the bacteria from the ESKPAE group. The ...

    Development of New Multicomponent Processes based on Unexplored Chemistry of Isocyanides: Access to Heterocyclic Scaffolds and Applications 

    Ghashghaei, Ouldouz (Date of defense: 2017-09-26)

    1. It was observed that the interaction of imines and isocyanides in the presence of a Lewis acid can lead to a variety of scaffolds including α-aminoamides, α-aminoamidines, indoles and diiminoazetidines. The reaction ...

    Development of New Tools for the Synthesis of "Difficult Peptides" 

    Paradís Bas, Marta (Date of defense: 2015-05-15)

    The known as "difficult peptides", as well as those sequences that aggregate in solution, are some of those molecules with high applicability as nanomaterials or even in medicine field. This thesis has addressed to overcome ...

    The development of new, direct and asymmetric Ni(II) catalysed carbon-carbon bond forming reactions and their application to total synthesis 

    Kennington, Stuart (Date of defense: 2020-12-21)

    This thesis focuses on the search for new methodologies for the direct, stereoselective and catalytic formation of carbon-carbon bonds through the formation of chiral nickel(II) enolate species and the application of such ...

    Development of novel EELS methods to unveil nanoparticle properties 

    Torruella Besa, Pau (Date of defense: 2019-04-26)

    [eng] The aim of this thesis has been two-fold. First, to develop new processing and analysis tools and strategies for extracting information from EELS data, and second, to apply the methods to different nanoparticle systems ...

    Development of novel electroactive nanofluids for flow cells 

    Rueda García, Daniel (Date of defense: 2020-09-15)

    Flow cells are on their way to become a key player for electrical energy storage (EES) thanks to their suitability as load-levelling devices thus contributing to the development of smart grid and to offset the intermittency ...

    Development of novel nanomedicines based on polyurethane-polyurea hybrid nanocapsules for cancer theragnosis 

    Bonelli Blasco, Joaquin Daniel (Date of defense: 2022-12-14)

    [eng] Nanomedicine is one of the cutting-edge fields in most of medical applications, specially, in oncology. The possibility to selectively vehiculize and specifically release a wide range of anticancer compounds gained ...

    Development of numerical methods to determine the litospheic structure combining geopetential, litosthatic and heat transport equations. Application to the Gibraltar arc system. 

    Fullea Urchulutegui, Javier (Date of defense: 2008-01-25)

    Detailed modelling of the present-day lithospheric structure is of paramount importance to understand the evolution of the Earth in the context of plate tectonics. The objectives of this thesis are twofold: the development ...