Browsing Universitat de Barcelona by Title

Development and regeneration of Drosophila wing imaginal discs: the role of IncRNAs and the stress sensor D-GADD45

Camilleri Robles, Carlos (Date of defense: 2022-07-22)

Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides that lack protein-coding potential. Although multiple examples of functional lncRNAs have been described, particularly regulating gene ...

Development and Validation of a Clinic Screening Tool to Improve Clinical Management of Symptoms and Health-related Concerns in People Living with HIV in Spain

Safreed Harmon, Kelly (Date of defense: 2022-03-09)

INTRODUCTION: Almost 38 million people were living with HIV at the end of 2020, 73% of whom were estimated to be receiving antiretroviral therapy (ART). The face of HIV has changed greatly since the first highly effective ...

Development and validation of a sequencing panel for translocations, copy number alterations and mutations with clinical relevance in mature B-cell neoplasms

Gómez Llonin, Andrea (Date of defense: 2021-04-30)

The application of NGS techniques to the study of mature B-cell neoplasms at the research level is providing a large amount of new information, in certain cases with clinical implications, which includes the identification ...

Development of 3D in vitro platforms for the study of muscle function and axonal growth and regeneration

Wells Cembrano, Karen Isabel (Date of defense: 2023-10-27)

[eng] The use of in vitro models in biomedical research offers an invaluable tool for exploring biological processes of health and disease. While animal models remain highly informative and necessary to ensure clinical ...

Development of a biomimetic mechanical stimulation system to improve the maturation of human iPS-derived myocardial grafts

Crespo Santiago, Juan (Date of defense: 2016-07-21)

La ingeniería tisular cardíaca ha evolucionado rápidamente en los últimos años, desde los primeros ensayos con diferentes especies animales hasta la producción de la primera generación de tejidos cardíacos humanos que ...

Development of a compact NDIR spectometer based on MOEMS components for fruit ripening monitoring

Fonollosa Magrinyà, Jordi (Date of defense: 2009-07-20)

[spa] Actualmente el control de la concentración de etileno en las cámaras de almacenamiento de fruta proporciona información de gran interés sobre su estado. Por un lado, la fruta produce pequeñas concentraciones de etileno ...

Development of a Complete Optical Microsystem for Particle Flow Detection

Bernat Ubiaga, Ivan (Date of defense: 2013-11-08)

Esta tesis doctoral resume el trabajo realizado en el Departamento de Electrónica de la Facultad de Física, en la Universidad de Barcelona. El objetivo de la misma se centra en el diseño y fabricación de un microsistema ...

Development of a divergent strategy towards the synthesis of lycopodium alkaloids

Saborit Villarroya, Gisela (Date of defense: 2016-07-19)

En la present tesi doctoral s’ha desenvolupat una estratègia per obtenir els esquelets dels quatre alcaloides licopodi representatius a partir d’un mateix intermedi sintètic comú 1, de manera semblant al procés que té lloc ...

Development of a multi-electrode impedimetric biosensor: detection of pathogenic bacteria and mycotoxins

Barreiros dos Santos, Marília (Date of defense: 2014-09-23)

This thesis aims the development of a multi-electrode platform with applications on different biosensing fields: (i) detection of pathogenic bacteria E.coli O157:H7 and (ii) detection of the mycotoxin Ochratoxin A. For ...

Development of a multichannel integrated circuit for Silicon Photo-Multiplier arrays readout

Comerma Montells, Albert (Date of defense: 2014-01-09)

The aim of this thesis is to present a solution for the readout of Silicon Photo-Multipliers (SiPMs) arrays improving currently implemented systems. Using as a starting point previous designs with similar objectives a novel ...

Development of a nano sensor for direct-electric free-label detection of DNA’s hybridization and single nucleotide polymorphism

Zafﬁno, Rosa Letizia (Date of defense: 2015-11-11)

The search for analytical tools suitable for wide-scale application of DNA analysis is an hot research topic, although thanks to well-established microarray based technology, analysis of DNA sequences and SNP detection can ...

Development of a Nano-Illumination Microscope

Franch Masdeu, Nil (Date of defense: 2022-07-21)

This doctoral thesis proposes and explores a new approach to lensless microscopy, focusing on making high resolution imaging ubiquitous and low cost. A short introduction to microscopy frames the state of current techniques: ...

Development of a New Parallel Code for 3-D Joint Refraction and Reflection Travel-Time Tomography of Wide-Angle Seismic Data. Synthetic and Real Data Applications to the Study of Subduction Zones

Meléndez i Catalán, Adrià (Date of defense: 2014-12-19)

This dissertation is devoted to seismic tomography. I have implemented a new modelling tool for 3-D joint refraction and reflection travel-time tomography of wide-angle seismic data (TOMO3D). The reason behind this central ...

Development of a population pharmacokinetic model to determine the optimal doses of amikacin in the treatment of neonatal sepsis

Martínez Illamola, Silvia (Date of defense: 2013-02-01)

The aim of this study was to establish the population pharmacokinetics of amikacin in newborns from serum concentration data obtained during the routine therapeutic drug monitoring and to explore the influence of patient ...

Development of an advanced 3D culture system for human cardiac tissue engineering

Valls Margarit, Maria (Date of defense: 2017-07-07)

Ischemic heart disease is a major cause of human death worldwide owing to the heart minimal ability to repair following injury. Other than heart transplantation, there are currently no effective or long-lasting therapies ...

Development of an Ambient Intelligence Environment to improve Patient Safety in Critical Care

Corrêa Volpini, Bruna (Date of defense: 2021-12-13)

In the late 1990's, when sophisticated personal computers and electronic devices with miniaturized sensors were being mass produced, the concept of ambient intelligence (AmI) emerged. An environment ...

Development of Analytical Methodologies for Rapid Determination of Alpha and Beta Emitters by Liquid Scintillation Spectrometry in Water Samples

Fons Castells, Jordi (Date of defense: 2016-12-23)

In this thesis the development of different methodologies for the rapid determination of alpha and beta emitters by liquid scintillation spectrometry is described. The feasibility of PLS model construction for the decombolution ...