Mostrando ítems 5-24 de 85
Petit Roig, Elena (Fecha de defensa: 2019-10-29)
El VIH-1 segueix essent un dels problemes més greus de la sanitat pública mundial, especialment als països del tercer món. La fase més avançada de la infecció pel VIH és la SIDA (síndrome d’immunodeficiència adquirida). La ...
Reig Canyelles, Marta (Fecha de defensa: 2017-07-07)
This thesis deals with the preparation and characterization of novel organic semiconductors based on the carbazole heterocycle for electronic and optoelectronic applications, specifically to be studied as active layers in ...
Ordóñez Vivanco, Yadira (Fecha de defensa: 2016-09-16)
Sphingolipids (SLs) encompass a large and diverse family of lipids that are essential constituents of cellular membranes. In addition to their structural functions, SLs are also emerging as important signalling molecules ...
Casanovas Bayo, Berta (Fecha de defensa: 2018-06-12)
Amb l’objectiu d’obtenir materials moleculars amb una o més propietats físiques tals com magnètiques, luminescents i/o quirals en aquest treball s’han obtingut nous compostos de coordinació basats en metalls de transició, ...
Clavero Puyal, Pau (Fecha de defensa: 2016-07-25)
La Tesi tracta sobre la preparació i l’ús en catàlisi homogènia asimètrica de lligands fosforats quirals amb àtoms de fòsfor estereogènics. En primer lloc es descriu la preparació i caracterització de lligands monofosforats ...
Esquivias Bautista de Lisbona, Oriol (Fecha de defensa: 2023-11-17)
[eng] Carbohydrates, as the most abundant biomolecules, play a myriad of roles and functions in biological systems. Unlike the building blocks of proteins, amino acids, whose chemical structure can vary significantly, ...
Alonso Gil, Santiago (Fecha de defensa: 2017-07-12)
Carbohydrates are one of the most important biochemical molecules due to their role as energetic resource for non-photosynthetic organisms, cell-cell recognition and adhesion, protection of cell membranes of bacteria and ...
Faustino Brissos, Rosa Maria (Fecha de defensa: 2018-04-13)
The discovery of cisplatin and its successful use as chemotherapeutic agent have encouraged the development of metal-based anticancer molecules. The present doctoral research project includes three different chemistry ...
Rovira Vidal, Anna (Fecha de defensa: 2023-03-03)
[eng] In this Thesis, we have explored the applications in cancer diagnosis and therapy of COUPY fluorophores, a new family of compounds based on the coumarin structure and operating in the far-red to near infrared region ...
Lázaro Palacios, Ariadna (Fecha de defensa: 2023-05-05)
[eng] This Doctoral Thesis is focused on the synthesis of cyclometallated platinum compounds with different structural modifications rationally designed specifically for biological or optical applications. Specifically, ...
López Barallobre, Blanca (Fecha de defensa: 2016-09-21)
Posar al mercat un nou fàrmac és un procés molt llarg i costós i que comporta un risc econòmic important per una empresa farmacèutica. En canvi, el desenvolupament d'un procediment millorat per a la producció d'un fàrmac ...
Duran Corbera, Macarena (Fecha de defensa: 2021-09-30)
Investigacions recents en el camp de la biomedicina han demostrat que les interaccions entre pèptids i macromolècules com ara les proteïnes, modulen i regulen processos biològics importants com la memòria, la resposta a ...
Borilović, Ivana (Fecha de defensa: 2018-11-23)
Combining the judiciously designed bis−β-diketone and polypyrazolyl scaffolds with the crystal field effects on the 3d metal ions, this manuscript exposes different methods of selective preparation of new heterometallic ...
Salinas Uber, Jorge (Fecha de defensa: 2016-07-29)
One of the main objectives of this thesis was the synthesis of new chelating ligands containing a photochromic unit able to change its conformation upon light irradiation. This isomerization should serve to modify the ...
Bertran Junqué, Alexandra (Fecha de defensa: 2018-10-25)
Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases involved in the degradation of the extracellular matrix. They make a major contribution to the progression of a vast number of diseases, ...
Martínez Bascuñana, Alba (Fecha de defensa: 2023-09-01)
[eng] The use of supramolecular interactions in catalysis has been widely studied and exploited for the straightforward preparation of the backbones of an array of structurally diverse stereoselective catalysts. In addition ...
Dalmases Solé, Mariona (Fecha de defensa: 2019-02-08)
The size/shape dependent and unique physical and chemical properties presented by nanostructured materials have attracted great attention in several fields such as energy harvesting, optoelectronics and biomedicine, among ...
Solé Solé, Judith (Fecha de defensa: 2022-06-03)
Following the laws of evolution, bacteria are capable of slowly but inexorably acquiring resistance to antibiotic compounds that we have been using for decades. Therefore, bacteria that seemed harmless to most people (such ...
Diego Creixenti, Rosa (Fecha de defensa: 2022-01-21)
Spin crossover (SCO) complexes and single-molecule magnets (SMMs) are promising prototypes that can reach magnetic bistability within the molecular scale required for data storage. Despite the extensive library of versatile ...
Kennington, Stuart (Fecha de defensa: 2020-12-21)
This thesis focuses on the search for new methodologies for the direct, stereoselective and catalytic formation of carbon-carbon bonds through the formation of chiral nickel(II) enolate species and the application of such ...