Recent Submissions

New visible-light activated caging groups based on COUPY dyes for anticancer phototherapeutic applications 

López Corrales, Marta (Date of defense: 2025-10-10)

[eng] This doctoral thesis has addressed the study of several therapeutic applications against cancer of a new family of photolabile protective groups (PPGs) based on COUPY coumarins, photoactivated with visible light. First, ...

Metal catalysed asymmetric C–C bond forming reactions 

Galeote Martin, Oriol (Date of defense: 2024-12-12)

[eng] This thesis presents novel methodologies for asymmetric C–C bond forming reactions, focusing on catalytic approaches involving chiral nickel(II) complexes. Chapter I introduces a new approach to direct asymmetric ...

Síntesis total de la Anfidinolida B1 

Barnils Rodríguez-González, Cristian (Date of defense: 2025-03-07)

[spa] En esta Tesis Doctoral se ha estudiado la síntesis total de la Anfidinolida B1, un macrociclo de 26 miembros aislado por primera vez por Shimizu y colaboradores en 1994 en Santo Tomás, una de las Islas Vírgenes de ...

Heterobifunctional molecules: PROTACs and beyond 

Rafael Miguel, Sergi (Date of defense: 2025-04-11)

[eng] Our body is an intricate, well-organized structure formed by trillions of cells. Each one of these cells is a highly complex entity composed of thousands of biomolecules that enable it to carry out its functions. ...

Peptide-based approaches for the race against resistant bacteria 

Garcia Gros, Júlia (Date of defense: 2024-12-05)

[eng] Antimicrobial resistance to almost all available antibiotics is on the top ten list of global public health challenges of the World Health Organization. Each year, the deaths due to AMR infections achieve the alarming ...

Simulations of glycoside hydrolase and phosphorylase reaction mechanism: families GH20, GH29, GH129 and GH130 

Cuxart Sanchez, Irene (Date of defense: 2024-12-04)

[eng] The most abundant family of biomolecules on earth are carbohydrates. Also known as glycans, sugars or saccharides, are based on polyhydroxycarbonyl backbones with a vast array of chemical and structural modifications, ...

Exploiting heterometallic lanthanide complexes for technological applications: Quantum Computing, Optical Properties and Magnetic Refrigeration 

Maniaki, Diamantoula (Date of defense: 2024-11-29)

[eng] This thesis explores the design and synthesis of molecular heterometallic lanthanide coordination compounds, highlighting their potential applications in quantum computing, as light-emitting devices, and for magnetic ...

Synthesis, deposition and characterization of magnetic molecules on surfaces 

Gabarró Riera, Guillem (Date of defense: 2024-11-12)

[eng] This doctoral thesis is dedicated to studying the synthesis and deposition of compounds with interesting magnetic properties on surfaces from an experimental perspective. The compounds studied are coordination compounds ...

Optimització de processos en la industria farmacèutica 

Cuesta Turienzo, Víctor (Date of defense: 2024-11-21)

[cat] La indústria farmacèutica ha exercit un impacte profund en la salut global durant les últimes dècades, contribuint de manera significativa a l'augment de l’esperança de vida. La seva missió principal és el desenvolupament ...

Multiproperty materials: luminescent and/or magnetic coordination compounds containing f-block elements. Chirality 

Tubau Ribot, Ànnia (Date of defense: 2024-09-20)

[eng] The main goal of this Thesis work is the obtention of new lanthanide(III) coordination compounds presenting luminescence and magnetic properties, hence presenting multiproperty behavior. Moreover, by inducing chirality ...

Triplet harvesting of gold(I) supramolecular complexes and their applications 

Aquino Samper, Araceli de (Date of defense: 2024-10-25)

[eng] This thesis has been done under the supervision of Prof. Laura Rodríguez (Inorganic Chemistry Section, Universitat de Barcelona) and Prof. João Carlos Lima (LAQV REQUIMTE, Universidade Nova de Lisboa). Over these ...

Síntesi d’un pèptid terapèutic: Un estudi metodològic vers la producció a escala de planta pilot 

Teruel Sánchez, Carolina (Date of defense: 2023-12-12)

[cat] Tradicionalment, els fàrmacs de baix pes molecular (PM < 500 Da), coneguts com “molècules petites”, han predominat en el tractament de les malalties humanes, encara que en les últimes dècades els productes biològics ...

Self-assembled molecules as efficient selective contacts in translucent quantum-dot light emitting diodes 

Kumari, Sarika (Date of defense: 2023-12-20)

[eng] Since the last two decades, nanotechnology has been revolutionary for representing small solutions to the big problems. Nanoscience and Nanotechnology spread from the area of Electronics, Energy and Environment to ...

Computational insights into carbohydrate epimerase mechanisms 

Esquivias Bautista de Lisbona, Oriol (Date of defense: 2023-11-17)

[eng] Carbohydrates, as the most abundant biomolecules, play a myriad of roles and functions in biological systems. Unlike the building blocks of proteins, amino acids, whose chemical structure can vary significantly, ...

Fighting bacteria. Synthesis and study of Polymyxin derivates to improve their therapeutic properties 

Pascual i Pérez, Marina (Date of defense: 2023-11-10)

[eng] Multidrug resistant bacteria have grown to be a significant medical concern as a result of decades of excessive antibiotic usage and overuse in human medicine, agriculture, and the animal industry. In this context, ...

Advances in Asymmetric Catalytic Reactions: Novel Methodologies and Synthetic Applications 

Bellido Muñoz, Marina (Date of defense: 2023-11-03)

[eng] This doctoral thesis aims to explore various synthetic methodologies and their corresponding applications in the field of asymmetric catalysis. More specifically, we have focused on the preparation of prochiral ...

Synthesis and Magnetic Studies of Quasi-Isotropic Coordination Compounds with 3d and 4f cations 

Pilichos, Evangelos (Date of defense: 2023-09-22)

[eng] The present Thesis is entitled “Synthesis and Magnetic Studies of Quasi-Isotropic Coordination Compounds with 3d and 4f cations”. The topic of the Thesis is to prepare coordination compounds of paramagnetic metal ...

Design of Catalytic Systems based on Halogen Bonding Interactions: Synthesis and Application in Catalytic Reactions 

Martínez Bascuñana, Alba (Date of defense: 2023-09-01)

[eng] The use of supramolecular interactions in catalysis has been widely studied and exploited for the straightforward preparation of the backbones of an array of structurally diverse stereoselective catalysts. In addition ...

Exploring the heavy atom effect and supramolecular assemblies of Au(I) and Pt(II) complexes 

Romo Islas, Guillermo (Date of defense: 2023-07-14)

[eng] This thesis is mainly focused on studying the photophysical properties of Au(I), Ag(I), Cu(I), and Pt(II) coordinated compounds. This work can be divided into two parts: on the one hand, the compounds of the group ...

Synthesis and characterization of multinary group 10-11 metal-based nanocrystals 

Lin, Mengxi (Date of defense: 2023-07-17)

[eng] Nanostructured semiconductors have gained significant importance due to their size- and morphology-tunable physical properties, and their ability to play a critical role in various fields such as energy conversion ...