Mostrando ítems 21-40 de 54
Caparrós Rodríguez, Francisco Javier (Fecha de defensa: 2018-07-06)
Les nanopartícules de metalls nobles han atret l’interès dels investigadors en els últims anys degut a la seva elevada activitat i selectivitat en un gran nombre de reaccions catalítiques. No obstant això, les nanopartícules ...
Mohammad Jabeen, Irrem Laareb (Fecha de defensa: 2021-09-23)
c-Src is a non-receptor tyrosine kinase that controls numerous cellular signaling pathways. c-Src implication in human cancers was brought into the attention in the 1980s. Since its discovery, unveiling of c-Src ...
Coines Lopez-Nieto, Juan (Fecha de defensa: 2021-01-20)
Carbohydrates are essential molecules in biotechnology and for the proper functioning of living organisms. They are involved in energy storage, being structural components or participating in crucial biological processes ...
Cuscó Marigó, Cristina (Fecha de defensa: 2018-03-22)
The Thesis is based on the development of a potentially-scalable methodology to prepare polyurethane/polyurea polymers to nanoencapsulate bioactive molecules. In the first part of the project, the design, optimization and ...
Cabré Montesinos, Albert (Fecha de defensa: 2020-01-31)
The main contribution of this doctoral thesis has been devoted to the field of synthetic organic chemistry. The Pauson-Khand reaction (PKR) is a metal-catalyzed [2+2+1] cycloaddition between an alkyne, an alkene and a ...
Bujaldón Carbó, Roger (Fecha de defensa: 2022-11-22)
[eng] The increasing demand on next-generation displays encourages an exhaustive research on the development of new and enhanced semiconductors. Apart from the conventional inorganic materials, organic-based semiconductors ...
Tolrà Rovira, Roser (Fecha de defensa: 2017-07-21)
L'objectiu principal d'aquesta Tesi doctoral ha estat l’obtenció d’una via alternativa a les existents per a l'obtenció d'un intermedi clau, 1, en la síntesi d'un fàrmac anticoagulant. La nova via havia de ser novedosa i ...
Segovia Laserna, Rosario (Fecha de defensa: 2022-03-08)
After decades of exorbitant antibiotic misuse and overuse in human medicine, agriculture and livestock industry, multidrug resistant bacteria (MDR) have become a major medical concern. In this regard, the design of new, ...
Gandioso Ubieto, Albert (Fecha de defensa: 2018-11-12)
In the present Thesis, it has been carried out the development of new chemical tools for the diagnosis and treatment of cancer through the use of light as an external factor. On the one hand, light can be used to control, ...
Arbesú Andrés, Miguel (Fecha de defensa: 2018-03-02)
c-Src is a central player in several cellular signaling pathways. It controls impor- tant cellular processes like cellular proliferation, survival or motility. Therefore, a number of tumoral diseases have been related to ...
San Juan Ocete, Alexis (Fecha de defensa: 2018-07-13)
Estudios previos de nuestro grupo de investigación describieron moléculas orgánicas heterocíclicas, aparentemente de capas cerradas que presentan carácter birradical triplete asequible térmicamente. La formación de esta ...
Vázquez Bigas, Guillem (Fecha de defensa: 2019-03-22)
Alzheimer’s disease (AD), for which no cure is known yet, is currently the most prevalent cause of dementia for the elderly population. The aberrant aggregation of β-amyloid peptide (Aβ) is believed to trigger the events ...
Arribas Crovara, Maria Fernanda (Fecha de defensa: 2022-11-11)
[spa] En el primer bloque de la tesis describimos nuestra aproximación a la síntesis total de la Palmerolida D, un compuesto de gran interés, tanto por sus propiedades antitumorales como por la diversidad de reacciones ...
Carneros García, Héctor (Fecha de defensa: 2018-06-29)
El desarrollo de métodos para la creación de nuevos enlaces carbono-carbono de forma sostenible y selectiva es clave en la química orgánica actual. En las últimas décadas, ha aumentado de gran manera el interés en llevar ...
Arlegui Chamizo, Aitor (Fecha de defensa: 2019-12-16)
La quiralidad es una propiedad fundamental de la naturaleza. La vida en la Tierra se basa en la quiralidad. Casi todos los compuestos quirales presentes en los organismos vivos se encuentran solo en una de sus formas ...
Salomó i Prat, Ernest (Fecha de defensa: 2018-10-19)
Asymmetric hydrogenation of double bonds by means of organometallic catalysis is a powerful tool for organic synthesis; it is an efficient and simple method to produce valued chiral compounds. Among the many different ...
Gallen Ortiz, Albert (Fecha de defensa: 2019-02-01)
The Thesis deals with the preparation, coordination chemistry and use in asymmetric homogeneous catalysis of several optically pure P-stereogenic ligands containing a tert-butylmethylphosphino fragment. In the first part ...
Rojo Solé, Josep Maria (Fecha de defensa: 2022-11-02)
[eng] P-Stereogenic ligands have demonstrated to be highly efficient for asymmetric catalysis, especially in metal-catalyzed asymmetric hydrogenation reactions. Among them, those bearing bulky substituents at phosphorus ...
Mancinelli, Andrea (Fecha de defensa: 2017-04-21)
The development of selective methods for the direct conversion of carbon−hydrogen bonds into carbon-heteroatom and carbon−carbon bonds remains a critical challenge in organic chemistry. An interesting approach to address ...
Llorens Palomo, Lluís (Fecha de defensa: 2019-10-28)
Cucurbiturils are known to present potential applications in molecular recognition, self- assembly, and nanotechnology. The discovery of ultra-high affinity CB–guest complexes with binding constant values similar than those ...