Rodríguez Vaello, Victoria Eugenia (Date of defense: 2020-12-11)
A fundamental step in embryo development is the transition through pluripotency. There are two known sequential states of pluripotency termed naïve and primed pluripotency. Considerable efforts have ...
Català Moll, Francisco (Date of defense: 2020-06-08)
Epigenetic factors, such as histone post-translational modifications and DNA methylation, are critical determinants of gene expression, which ultimately defines cell identity and function. Despite intense ...
Olival T., Jonathan F. (Date of defense: 2022-10-20)
[eng] Neonatal arterial ischemic stroke (NAIS) is a cerebrovascular disease that shows a focal disruption of cerebral blood flow due to artery obstruction. Due to its early onset, it can cause long-lasting ...
Norris, Richard (Date of defense: 2021-10-13)
Insulinomas are extremely rare pancreatic neuroendocrine (PNET) tumours that develop from the β-cells of the pancreas.β-cells are the only cells capable of producing the hormine insulin, and play a major ...
Menéndez Serra, Mateu (Date of defense: 2022-06-16)
Understanding the mechanisms and processes driving biological com- munities assembly, i.e. determining why a specific community is found under certain circumstances, is one of the fundamental questions ...
Barranco Muñoz, Neus (Date of defense: 2020-06-22)
The regulated secretory pathway is a hallmark of professional secretory cells as neurons and endocrine cells. Significant peptidergic neurotransmitters as hormones, neurotrophins and growth factors ...
Calucho Prim, Maite (Date of defense: 2021-11-24)
La Fibrosis Quística (FQ) es una enfermedad autosómica recesiva que ocurre cuando existen variantes patogénicas bialélicas en el gen Cystic Fibrosis Transembrane Regulator (CFTR), y que codifica por una ...
Michel Todó, Lucas (Date of defense: 2023-03-28)
[eng] The most severe form of malaria, caused by Plasmodium falciparum parasites, still kills over half a million people every year, most of them children under the age of five. Despite huge research ...
Solá Castrillo, Paloma (Date of defense: 2023-05-25)
[eng] Aging can be defined as a decline or loss of adaptation during the increase of age, caused by a progressive deterioration of functions and integrity. This occurs in tissues such as the skin, which ...
Pena Rodríguez, Eloy (Date of defense: 2022-07-18)
[eng] Different transdermal drug delivery platforms have been developed for epidermal and follicular targeting. Nanoformulations have been developed, optimised and physicochemically characterised with ...