Planas Fèlix, Mercè (Date of defense: 2020-10-05)
The identification and analysis of genomic variation across individuals has been central in biology, first through comparative genomics to answer evolutionary questions, and then in the context of ...
Antich González, Adrià (Date of defense: 2022-10-24)
[eng] Ecosystem biomonitoring is crucial for proper management of natural communities during the Anthropocene era. With the advent of new sequencing technologies, DNA metabarcoding has been proposed as ...
Paredes Fuentes, Abraham José (Date of defense: 2022-12-01)
[spa] El objetivo general de este trabajo de tesis doctoral ha sido progresar en el desarrollo de biomarcadores para el estudio de pacientes con enfermedades mitocondriales. Los objetivos concretos han ...
Benítez Amaro, Aleyda (Date of defense: 2022-12-22)
[eng] BACKGROUND: Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid metabolism and glucose homeostasis. In the context of dyslipidemia, LRP1 is positively regulated ...
Soto Montañez, Carlos Antonio (Date of defense: 2021-03-18)
Las personas con insuficiencia renal crónica (ERC) suelen manifestar sentirse más fatigados al terminar la sesión de diálisis (HD). Cabe destacar que se trata de una población compuesta por pacientes ...
Fernández Carasa, Irene (Date of defense: 2021-06-29)
Parkinson’s disease (PD) is an incurable, chronically progressive disorder of old age leading to premature invalidity and death. Clinically, PD is characterized by classical motor syndrome linked to a ...
Marin Guillen, Ines (Date of defense: 2023-04-20)
[eng] Cellular senescence is a response to stress and damage, ant it is known to activate innate immune cells. However, the mechanisms by which senescent cells interact with the adaptive arm of the ...
Valdivieso Muñoz, Alejandro (Date of defense: 2020-03-05)
In many organisms, sex is determined by a combination of genetic and environmental influences. Epigenetic regulatory mechanisms such as DNA methylation integrate both types of influences. However, ...
Silva, Rui Gonçalo Teixeira da (Date of defense: 2022-09-16)
Steatotic livers are considerably more prone to IRI, in which turn, it is known to impair mitochondrial function. Our working hypothesis lies on the fact that impaired mitochondrial function and reduced ...
Gómez Bardallo, Raquel (Date of defense: 2023-03-10)
[spa] La lesión por isquemia-reperfusión (IR) es la mayor causa de pérdida y disfunción de tejidos y órganos en trasplantes clínicos, como es el trasplante hepático. Durante la isquemia, la carencia de ...