Mostrando ítems 2491-2510 de 11039

    Desenvolupament industrial i clusterització. La indústria càrnia porcina a Catalunya, segles XIX i XX 

    Castell Castells, Pere (Fecha de defensa: 2022-11-11)

    [cat] Aquesta recerca analitza la indústria càrnia porcina catalana durant els segles XIX i XX. Identifica els principals factors que han condicionat el seu desenvolupament i les dinàmiques de localització geogràfica en ...

    Desenvolupament neuropsicològic infantil i competències ètiques. Una proposta educativa des de la neuroètica 

    Navarro Pons, Sandra (Fecha de defensa: 2019-05-25)

    INTRODUCCIÓ: Els coneixements actuals en neuroeducació i neuroètica ens animen a estimular el desenvolupament de funcions cerebrals facilitadores d’habilitats cognitives, emocionals i socials que ens permeten millorar la ...

    Desenvolupament, caracterització i avaluació d’una nova forma farmacèutica basada en micro-comprimits d’alliberació modificada 

    Ruiz Xivillé, Núria (Fecha de defensa: 2019-10-07)

    El metilfenidat HCl (MPH) és un fàrmac clàssic per al tractament del TDAH en nens a partir dels 6 anys, quan altres mesures resulten insuficients. Aquest trastorn es manifesta principalment durant la infància i l’adolescència ...

    Desenvolupament, caracterització i avaluació in vitro-ex vivo de noves formulacions tòpiques pel tractament de la leishmaniosi cutània 

    Pujol Brugués, Alba (Fecha de defensa: 2015-01-23)

    La leishmaniosi constitueix un conjunt de malalties causades per diferents espècies del gènere Leishmania que presenten diferents formes clíniques depenent de l’espècie, del seu tropisme i de la resposta immune de l’hoste. ...

    Design and characterization of topical ketorolac tromethamine formulations 

    El Moussaoui El Masnaoui, Salima (Fecha de defensa: 2022-10-26)

    [eng] Pain and inflammation are the most common and recurrent side effects after surgery and, understandably, the patient's most feared, affecting treatment adherence. The present work aims to characterize in vitro, ex ...

    Design and Engineering of Advanced Cathode Hosts for Lithium-Sulfur Batteries 

    Zhang, Chaoqi (Fecha de defensa: 2022-07-04)

    Lithium-sulfur batteries (LSBs) are regarded as the most promising candidate to replace Lithium-ion batteries (LIBs) in next-generation energy storage systems. Compared with LIBs, LSBs are characterized by a sixfold higher ...

    Design and evaluation of navigation and control algorithms for spacecraft formation flying missions 

    Perea Virgili, Laura (Fecha de defensa: 2010-05-21)

    Formation flying offers space-dependent disciplines such as astrophysics, astrodynamics, and geodesy, to name a few, the possibility of creating large spaceborne sensors from an array of small spacecraft flying in formation. ...

    Design and preparation of functional coordination compounds based on poly-β-diketone and polypyrazolyl ligands 

    Borilović, Ivana (Fecha de defensa: 2018-11-23)

    Combining the judiciously designed bis−β-diketone and polypyrazolyl scaffolds with the crystal field effects on the 3d metal ions, this manuscript exposes different methods of selective preparation of new heterometallic ...

    Design and Synthesis of Bifunctional Compounds for Targeted Protein Degradation and Phosphorylation 

    Loren Parrondo, Guillem (Fecha de defensa: 2023-09-15)

    [eng] In this doctoral thesis, the design and synthesis of bifunctional molecules that induce the degradation of a target protein in cells are described. The synthesis of molecules capable of inducing the phosphorylation ...

    Design and synthesis of engineered peptides to target undruggable PPIs: from in silico to in vitro studies 

    Rivas Santos, Pep (Fecha de defensa: 2019-12-10)

    Major unsolved diseases such as Cancer, cardiopathies or neurodegenerative disorders are frequently related with the malunction of complex protein networks. These networks are integrated by the interaction of multiple ...

    Design and synthesis of heterocyclic compounds potentially antitumor by enzymatic inhibition 

    Lizano Gispert, Enric (Fecha de defensa: 2020-07-24)

    This doctoral thesis is focused on the investigation and development of new compounds directed to different cancer and tropical diseases targets. Drug resistance, as well in cancer as in tropical diseases, is a hurdle which ...

    Design and synthesis of new potentially inhibitors of PCSK9 and KRAS proteins 

    Vilaplana Saiz, Marta (Fecha de defensa: 2021-01-22)

    This thesis shows the research carried out on two specific diseases: familial hypercholesterolemia, which is included within the cardiovascular diseases group, and cancer. These diseases are the major cause of deaths in ...

    Design and synthesis of peptides that neutralize bacterial endotoxins as therapeutic agents for the treatment of sepsis 

    Mas Moruno, Carlos (Fecha de defensa: 2009-03-05)

    La sepsis es un síndrome muy complejo de definir, diagnosticar y tratar. La patología de la sepsis se deriva de una respuesta perjudicial del organismo a una infección. La exposición a endotoxinas bacterianas induce una ...

    Design and synthesis of photoswitchable coordination complexes 

    Salinas Uber, Jorge (Fecha de defensa: 2016-07-29)

    One of the main objectives of this thesis was the synthesis of new chelating ligands containing a photochromic unit able to change its conformation upon light irradiation. This isomerization should serve to modify the ...

    Design and synthesis of selective MMP-9 inhibitors for the treatment of epilepsy 

    Bertran Junqué, Alexandra (Fecha de defensa: 2018-10-25)

    Matrix metalloproteinases (MMPs) are a family of zinc-containing endopeptidases involved in the degradation of the extracellular matrix. They make a major contribution to the progression of a vast number of diseases, ...

    Design and synthesis of sphingosine-1-phosphate lyase inhibitors and fluorogenic probes for the development of HTS assays 

    Sanllehí Figuerola, Pol (Fecha de defensa: 2016-11-02)

    Sphingolipids (SLs) are essential structural and signaling molecules of eukaryotic cells. An important group of SLs metabolites are those showing a phosphate group at the C1‒ OH. Among them, sphingosine‒1‒phosphate (S1P) ...

    Design de candeeiros de iluminação pública para a a sustenibilidade do espaço público 

    Águas, Sofía (Fecha de defensa: 2009-01-01)

    O:<br/><br/>O presente trabalho investiga os processos de design apropriados à eco-concepção de candeeiros de iluminação pública que possam contribuir para a sustentabilidade do espaço público urbano em geral. <br/>A ...

    Design of bioinformatic tools for integrative analysis of microRNA-mRNA interactome applied to digestive cancers 

    Vila Casadesús, Maria (Fecha de defensa: 2017-09-05)

    En esta tesis se han desarrollado e implementado distintas herramientas bioinformáticas que permiten el estudio de las interacciones miRNA-mRNA en contextos celulares específicos. oncretamente se ha creado un paquete de R ...

    Design of Catalytic Systems based on Halogen Bonding Interactions: Synthesis and Application in Catalytic Reactions 

    Martínez Bascuñana, Alba (Fecha de defensa: 2023-09-01)

    [eng] The use of supramolecular interactions in catalysis has been widely studied and exploited for the straightforward preparation of the backbones of an array of structurally diverse stereoselective catalysts. In addition ...

    Design of Homogenous Territorial Units. A Methodological Proposal and Applications 

    Duque Cardona, Juan Carlos (Fecha de defensa: 2004-09-30)

    The interest in geographical information technologies has grown considerably over the last three decades. Today, geographical information is no longer the exclusive domain of government and public administrations (in the ...