Mayorgas, Aida (Date of defense: 2021-09-08)
Inflammatory bowel disorders – such as Inflammatory Bowel Disease (IBD) – are rising worldwide. A well-known feature of IBD is dysbiosis of the gut microbiota, characterized by a significant reduction ...
Zapata Garin, Claire-Alix (Date of defense: 2018-06-01)
Glycogen is a branched polysaccharide that serves as an intracellular store of glucose that can be mobilized to maintain homeostasis or to fuel cellular processes. Glycogen is synthesized by glycogen ...
Gutiérrez García, Laura (Date of defense: 2019-10-31)
In plants, the sterol biosynthetic pathway leads to the production of a complex mixture of end-products, among which β-sitosterol, stigmasterol, campesterol, and cholesterol are the most abundant ones. ...
González Pérez, Laura (Date of defense: 2019-12-12)
The cell cycle is orchestrated by the periodic activation of Cyclin-dependent kinases (CDKs). The enzymatic activity of CDKs depends on their association with cyclins, however, in some cases these kinases ...
di Domenico, Angelique (Date of defense: 2017-12-18)
La malaltia de Parkinson (PD) s'associa amb la degeneració de les neurones dopaminèrgiques del mesencèfal ventral (vmDA) i l'acumulació d'inclusions citoplasmàtiques, els cossos de Lewy, compostos ...
Garcia Carbonell, Ricard (Date of defense: 2017-12-22)
Inflammatory bowel diseases (IBD) are chronic inflammatory processes that affect the gastrointestinal tract. IBD is characterized by an intestinal inflammation and epithelial cell injury leading to a ...
Marín-Valls, Roser (Date of defense: 2021-10-01)
Biocatalysis gained importance in the latter half of the 20th century and its application in the pharmaceutical, food and chemical industries continues to expand nowadays. Enzymes catalyze chemical ...
Moizé Arcone, Violeta (Date of defense: 2017-09-14)
BACKGROUND: Bariatric surgery (BS) is the most effective long-term therapy for the treatment of severe obesity. Benefits of BS include a reduction of overall and cardiovascular mortality, incidence of ...
Scaffidi, Salvatore (Date of defense: 2021-01-15)
Once a target is identified and characterized, the long pathway to develop a drug starts. In this process, biophysical methods have an important part to play and nowadays are firmly combined at several ...
Alves Figueiredo, Hugo Jorge (Date of defense: 2018-06-29)
El trasplante de islotes ha sido reconocido como una prometedora opción de tratamiento de la diabetes tipo 1 (DT1) tras la introducción del protocolo de Edmonton, el cual enfatiza el requerimiento de ...