Deniz, Ozgen (Date of defense: 2014-05-06)
The nucleosome is the fundamental structural unit of DNA compaction in eukaryotic cells and is formed by the wrapping of 147 bp double stranded DNA around a histone octamer. Nucleosome organization plays ...
Casasampere Ferrer, Mireia (Date of defense: 2017-03-24)
Els esfingolípids són lípids complexes derivats de l’esfingosina que a més de servir de base estructural de les membranes cel·lulars, regulen múltiples vies de senyalització, com per exemple l’autofàgia. ...
Arroyo Sánchez, Rodrigo (Date of defense: 2014-06-20)
Network and systems biology disciplines could revolutionize the study of complex diseases by taking proteins back to their context, considering a much broader perspective of their environment without ...
Pinacho Garcia, Raquel (Date of defense: 2015-07-17)
Psychotic disorders including bipolar disorder and schizophrenia are a leading cause of disability across the world but the underlying pathophysiological mechanisms remain poorly understood. Available ...
Dimastrogiovanni, Giorgio (Date of defense: 2015-09-18)
Many chemicals are continuously entering into the aquatic environment, as a result of their widespread use, disposal and accidental release. Several of these xenobiotics may disrupt reproductive functions ...
Gonzàlez Juncà, Alba (Date of defense: 2013-11-15)
The TGF-beta oncogenic effect has been widely studied. In glioma, TGF-beta has an oncogenic role increasing cell proliferation and glioma-initiating cell (GIC) self-renewal capacity. During the investigation ...
Turón Rodrigo, Gemma (Date of defense: 2019-04-25)
Colorectal tumors are not homogeneous entities but rather composed of a mixture of cells with different phenotypes, reminiscent of healthy intestinal epithelium cell types. Intestinal epithelium is one ...
Pagès Fauria, Jordi (Date of defense: 2013-09-16)
Overall, this thesis aims at approaching macrophyte herbivory and community ecology from a behavioural landscape perspective. Our study system, the seascape mosaic of Posidonia oceanica seagrass meadows ...
Pentinat Pelegrin, Thais (Date of defense: 2013-12-17)
Es coneix que la nutrició en les primeres etapes de la vida és un factor clau que contribueix a la prevalença de la obesitat, així com la resta de característiques de la Síndrome Metabòlica en l’edat ...
Aragón Altarriba, Eric (Date of defense: 2013-12-13)
Cell fate is controlled by a multitude of signals and loss of this control has devastating consequences for living organisms. One of the key players in this network of signals is the TGF-beta family of ...