Now showing items 171-190 of 229
Ventayol Espinazo, Marina (Date of defense: 2013-02-22)
Les patologies renals s’han convertit en una problemàtica a nivell mundial, en l’actualitat poden afectar a una de cada 9 persones al llarg de la seva vida i porten associats elevats costos econòmics. Malgrat els últims ...
Ivani, Iván (Date of defense: 2016-12-13)
Classical force fields are the core of classical simulations, particularly of molecular dynamics (MD), a technique that is changing our view on the structure, flexibility and function of biological macromolecules. Originated ...
Olivares Requena, Manuel (Date of defense: 2021-02-19)
Marine planktonic copepods play a key ecological role in pelagic food webs. The study of their patterns of activity is fundamental in order to better understand the processes involved in the transfer of energy from lower ...
Carella, Mirco (Date of defense: 2018-07-13)
The Antarctic bottoms harbour rich communities of sponges, which play an important role in structuring benthic habitats. Many Antarctic sponge species have been discovered in the past but most of them were poorly described ...
Pena Rodríguez, Eloy (Date of defense: 2022-07-18)
[eng] Different transdermal drug delivery platforms have been developed for epidermal and follicular targeting. Nanoformulations have been developed, optimised and physicochemically characterised with complementary techniques. ...
Soy Platero, Judit (Date of defense: 2014-07-17)
Arabidopsis thaliana seedling growth and development is influenced by both external (such as light and temperature) and internal (like hormones or circadian clock) factors. In short-day (SD) growing conditions, it is known ...
Peyre, Gwendolyn (Date of defense: 2015-05-12)
The páramo is a high mountain ecosystem that includes the natural and semi-natural habitats located between the montane treeline and the permanent snowline in the humid Northern Andes. Given its recent origin and continental ...
Fernández Alfara, Marcos (Date of defense: 2022-04-07)
Translation of mRNAs into proteins is a highly regulated step of gene expression. In cancer, post-transcriptional and translational control have a critical effect on transformation, controlling proliferation, survival, ...
Moreno Aguilera, Marcos (Date of defense: 2023-09-29)
[spa] El splicing alternativo es un proceso que además de proporcionar diversidad al transcriptoma y proteoma celular, añade una nueva capa de regulación en la expresión de proteínas y en la función que estas desempeñan. ...
Silva, Rui Gonçalo Teixeira da (Date of defense: 2022-09-16)
Steatotic livers are considerably more prone to IRI, in which turn, it is known to impair mitochondrial function. Our working hypothesis lies on the fact that impaired mitochondrial function and reduced protection against ...
Vera Montecinos, América (Date of defense: 2021-03-23)
Schizophrenia is a complex psychiatric disorder involving dysregulation of multiple pathways. In the last decades, the cortico-cerebellar-thalamo-cortical circuit has been proposed to play a key role in cognitive impairments ...
Catasús Segura, Núria (Date of defense: 2022-05-31)
Neurofibromatosis type 2 (NF2) is an autosomal dominant condition caused by loss of function variants in the NF2 gene. The pathognomonic feature of the disease is the development of bilateral vestibular schwannomas (VS), ...
Pedraz López, Lucas (Date of defense: 2020-01-13)
The perpetuation of life depends on the ability to reproduce. All known forms of life use DNA as genetic information storage. Ribonucleotide reduction is the process by which ribonucleotides (NTPs) are transformed into ...
Dimastrogiovanni, Giorgio (Date of defense: 2015-09-18)
Many chemicals are continuously entering into the aquatic environment, as a result of their widespread use, disposal and accidental release. Several of these xenobiotics may disrupt reproductive functions of both vertebrates ...
Rodríguez Sánchez, Maria de los Ángeles (Date of defense: 2019-11-22)
Las proteínas insulator son componentes esenciales de la organización tridimensional de la cromatina ya que son capaces de establecer interacciones entre regiones distantes de la mediante su capacidad de asociarse a otras ...
Buñuel Moreno, Xavier (Date of defense: 2021-07-13)
The role of consumer-resource relationship is the basis of the structure and functioning of ecological communities. The traditional lens for studying such interactions have tended to omit the importance of the species ...
Rodríguez Muñoz, Laura (Date of defense: 2021-05-13)
The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor with key functions downstream of receptor tyrosine kinase (RTK)-Ras-MAPK signaling pathways. In both Drosophila and mammals, Cic is expressed as ...
Hereu Planellas, Mercè (Date of defense: 2019-07-19)
Modern lifestyles in an increasing number of human societies include consuming an excess of saturated fats and refined sugars as well as enjoying microbiologically aseptic environments. Maintaining the appropriate ...
Cuesta Borràs, Estefania (Date of defense: 2019-11-28)
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. Slow-cycling cancer ...
Trujillano Fernández, Alejandro (Date of defense: 2024-02-08)
[eng] DYRK1A is a kinase that is expressed in virtually all tissues and cell types and is implicated in human diseases. Several studies indicate that DYRK1A is a dose-dependent gene with a prevalent function in brain ...