Universitat de Barcelona
Now showing items 142-161 of 229
[eng] Cytoplasmic Polyadenylation Element Binding proteins (CPEBs) are a family of RNA-binding proteins that regulate cytoplasmic changes in poly(A) tail lengh and therefore mRNA-specific stability and translation. Since ...
[eng] Our understanding of the transcriptional control of cellular identity is rapidly emerging. Mediator complex enriches at active enhancers, forms a protein bridge to target genes, and recruits RNA Polymerase II ...
The Mediterranean Sea can be considered an excellent natural laboratory for benthic ecologists, due to its peculiar environmental conditions, its broad-scale gradients, and its deep-sea fauna. Primary production levels in ...
Esta tesis se ha enfocado en evaluar el potencial de mejora del control biológico por conservación en huertos frutales y hortícolas en Cataluña, mediante la integración de infraestructuras ecológicas que promuevan y ...
Els esfingolípids són lípids complexes derivats de l’esfingosina que a més de servir de base estructural de les membranes cel·lulars, regulen múltiples vies de senyalització, com per exemple l’autofàgia. Entre tots els ...
Colorectal cancer (CRC) kills around 700,000 people worldwide every year. The majority of these deaths are the result of dissemination of the disease to foreign organs. Despite undergoing curative resection of the primary ...
Systems Biology opens new frontiers in the studies of complex diseases such as Multiple Sclerosis (MS). The questions that couldn’t be addressed before due to lack of understanding and methodological base, such as the ...
Neurofibromatosis type 1 (NF1) is a genetic disease caused by inherited mutations in the NF1 gene. NF1 is a cancer predisposition syndrome, and the disease’s hallmark is the appearance of tumors of the peripheral nervous ...
Las células de la glía envolvente olfatoria surgen hace algunos años como una estrategia prometedora para reparar la médula espinal lesionada. Sin embargo, diversas moléculas inhibitorias están presentes durante largo ...
Despite decades of work, the molecular requirements underlying microtubule- organizing center (MTOC) formation at the centrosome remain obscure. Progress is hindered by the complexity of this organelle, which is composed ...
The main goal of this thesis was to investigate the function of the endogenous CD300f. Initially, CD300f was described as an inhibitory receptor, although some data generated in our lab strongly suggested the possibility ...
[eng] BACKGROUND: High-risk neuroblastoma (NB) represents a heterogeneous group of tumors, whereby patients can display response to treatment and long-term outcome or develop early progressive, chemoresistant disease with ...
Epigenetic factors, such as histone post-translational modifications and DNA methylation, are critical determinants of gene expression, which ultimately defines cell identity and function. Despite intense research in DNA ...
During the process of corticogenesis, cortical radial glial cells (RGs) generate sequentially most of the distinct types of neurons and glial cells that will populate the neocortex. The generation of these cells at the ...
La presente Tesis Doctoral está centrada en el centollo atlántico (Maja brachydactyla Balss, 1922). Los objetivos incluyen la optimización del cultivo larvario y el estudio ontogénico del sistema digestivo. El cultivo ...
The study of morphology of organisms has become a widely extended scientific discipline since the beginning of the 20th century, when the scientific community began to establish direct relationships between the anatomical ...
Breast cancer is a very heterogeneous disease with a poor prognostic outcome, largely due to its resistance to current cancer therapies. The balance between cell proliferation and apoptosis plays a critical role in determining ...
[eng] In the quest for understanding complex biological systems, the scientific community has been delving into protein, chemical and disease biology, populating biomedical databases with a wealth of data and knowledge. ...
[eng] BACKGROUND: Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid metabolism and glucose homeostasis. In the context of dyslipidemia, LRP1 is positively regulated in the heart. The ...
Els trastorns neuromusculars pediàtrics són malalties minoritàries causades per un gran nombre de gens, molts d’ells de gran mida i d’estructura complexa, fet que dificulta enormement el diagnòstic molecular i el disseny ...
