Oliveras Ferrarós, Cristina (Date of defense: 2013-06-21)
The aim of this doctoral thesis was to unravel mechanisms underlying primary resistance to trastuzumab regarding a putative new breast cancer subtype with mixed basal & ErbB2+ molecular features. Using ...
Bosch i Grau, Montserrat (Date of defense: 2003-12-18)
Amb la finalitat d'aprofundir en les bases moleculars de la citotoxicitat de les ribonucleases pancreàtiques, es van construir variants derivades de l'HP-RNasa seguint dues estratègies. En la primera, ...
Castillo Martín, Miriam (Date of defense: 2014-07-09)
In the present Thesis, we observed that vitrifying-warming porcine embryos had detrimental effects. Indeed, vitrification and warming were seen to reduce developmental ability and quality of in vitro ...
Marull Arnall, Anna (Date of defense: 2021-06-21)
Currently, automatic analyzers based on highly accurate methods can determine hematologic parameters in a fast and reliable way which is important to detect abnormalities in blood cells. In laboratories ...
Sepúlveda, Lilian (Date of defense: 2016-09-30)
Boar semen is not collected under sterile conditions,so boar ejaculates are commonly contaminated with a broad range of microorganisms, which may affect sperm quality and lead to a low reproductive ...
Casas Roqueta, Isabel (Date of defense: 2010-07-08)
L'ús d'esperma criopreservada en la inseminació artificial (IA) d'espècies d'interès productiu permet un major control sanitari i la creació de bancs de germoplasma d'alt valor genètic, entre d'altres ...
Mateo Otero, Yentel (Date of defense: 2023-06-13)
For many years, reproductive outcomes were considered as being solely determined by the genome of oocytes and sperm. Yet, in the last decades, many other female and male factors have also been found to ...
Bravo Bonilla, Marlon Rolando (Date of defense: 2022-06-16)
Cancer is the leading cause of death due to non-communicable diseases worldwide. Despite the advances in the development of new antitumor drugs, there are still problems such as the resistance that tumor ...
Viñolas Vergés, Estel (Date of defense: 2023-07-27)
Male fertilising capacity has traditionally been predicted by the assessment of sperm concentration, motility and morphology. During the last few decades, however, research has been particularly focused ...
Miró Domènech, Laura (Date of defense: 2023-01-13)
Pancreatic ductal adenocarcinoma (PDA) presents a dismal prognosis mainly due to its delayed diagnosis, its aggressiveness, and resistance to existing therapies. Aberrant glycosylation and, in particular, ...