Di Vona, Chiara (Date of defense: 2013-09-20)
The view on how protein kinases regulate gene expression have recently expanded to include not only transcription factors but also histones, chromatin remodelers or components of the basal transcription ...
Balbastre Català, Borja (Date of defense: 2022-10-27)
Dual-specificity tyrosine-regulated kinases (DYRKs) are a conserved family of protein kinases present in all eukaryotes. In mammals, the association of DYRKs with a wide variety of putative substrates ...
Salichs Fradera, Eulàlia (Date of defense: 2008-12-15)
PolyHistidine repeats and DYRK1A: from the localization to the function<br/>El principal objectiu d'aquesta tesi ha estat el d'esbrinar noves funcions de la proteína quinasa DYRK1A en el nucli cel.lular. ...
Boni, Jacopo (Date of defense: 2019-06-20)
DYRK (dual-specificity tyrosine-regulated kinases) is an evolutionary conserved family of protein kinases involved in the regulation of cellular processes, such as proliferation and survival, which play ...
Arató, Krisztina (Date of defense: 2010-12-20)
DYRK1A is the most studied member of the DYRK family of protein kinases, because is one of the human chromosoma 21 proteins for which changes in gene dosage result in neuropathological alterations. DYRKs ...
Barba Moreno, Laura (Date of defense: 2018-06-22)
DYRK1A (dual-specificity tyrosine-regulated kinase 1A) belongs to a conserved family of protein kinases present in all eukaryotes. DYRK1A is known to participate in cell proliferation and differentiation ...
Roewenstrunk, Julia Maria (Date of defense: 2016-12-19)
Gene dosage alterations of the kinase DYRK1A are linked to disease in humans. To better understand DYRK1A activities an interactome analysis was performed. RNF169, an E3-ubiquitin ligase key component ...
Cort, Rianne Angelica (Date of defense: 2019-12-13)
The kinase DYRK1A (dual-specificity tyrosine-regulated kinase 1A) is a dosage-sensitive gene, since both haploinsufficiency and overexpression when in trisomy lead to pathological phenotypes in humans. ...