Mostrando ítems 11-18 de 18
Oller Salvia, Benjamí (Fecha de defensa: 2015-05-18)
Brain delivery is a major unmet challenge because most drugs cannot cross the blood-brain barrier (BBB). Despite the restrictive nature of this barrier, brain vasculature reaches essentially every neural ...
Elduque Busquets, Xavier (Fecha de defensa: 2014-09-05)
This work is divided in 2 different parts: Part A: Cyclization and conjugation can confer on biomolecules better activity, resistance toward enzymatic degradation and better internalization ...
Mas Moruno, Carlos (Fecha de defensa: 2009-03-05)
La sepsis es un síndrome muy complejo de definir, diagnosticar y tratar. La patología de la sepsis se deriva de una respuesta perjudicial del organismo a una infección. La exposición a endotoxinas ...
Herraiz Cobo, Jesús (Fecha de defensa: 2017-07-13)
Mayotlide is a marine peptide isolated by PharmaMar S.A. from Spongia sp.. The sequence of the aminoacids were achieved by MS-MS spectrometry, where two of them were tryptophans. The NMR spectroscopy ...
Vila Farrés, Xavier (Fecha de defensa: 2014-11-14)
Nowadays in the world there is a very big problem associated with two factors related to each other. The first factor is the increase in the resistant of certain bacteria, especially the bacteria from ...
Fernández Arauzo, Leticia (Fecha de defensa: 2012-06-15)
El GB virus C (GBV-C), también conocido como virus de la hepatitis G, es un virus humano no patogénico. Su infección es bastante frecuente, encontrándose incluso en personas sanas. Su prevalencia es ...
Martín Gómez, Helena (Fecha de defensa: 2018-02-23)
Nowadays, the discovery and development of novel constrained peptides which are likely to combine the advantages of therapeutic proteins with those of small molecules is of special interest. This has ...
Arranz Gibert, Pol (Fecha de defensa: 2017-01-12)
The work of this thesis is based on research on peptides able to cross the blood-brain barrier and their use as tools to enable the delivery of drugs into the brain. The blood-brain barrier (BBB) is ...