Iacobucci, Simona (Date of defense: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural ...
Gholami, Behjat (Date of defense: 2017-09-18)
Osteoporosis is a general skeletal disorder. It is characterized by a low bone mass and a microarchitectural deterioration of bone tissue, which increase bone fragility and susceptibility to fracture. ...
Tamirlsa, Srlvldya (Date of defense: 2014-07-14)
La ciencia básica ha de engarzarse con las necesidades sociales. Así, nuestro laboratorio esta involucrado en identificar genes específicamente modulados durante el proceso de cicatrización mediante ...
Rivera Brugués, Núria (Date of defense: 2012-03-20)
Genomic microarray analysis is rapidly replacing conventional chromosome analysis by molecular karyotyping due to the significant increase in the power to detect causative CNVs. Here, we extensively ...
Castillo Andreo, David (Date of defense: 2023-03-01)
[eng] Microscopy and Chromosome Conformation Capture (3C) are the two main techniques for studying the three-dimensional (3D) organization of the genome. Microscopy, allowing the visualization of genomic ...
Torruella i Cortés, Guifré (Date of defense: 2014-12-19)
To understand the origin of opisthokonts or infer evolutionary transitions within the group that contains two multicellular lineages (animals and fungi), it is first fundamental to understand the ...
Planas Fèlix, Mercè (Date of defense: 2020-10-05)
The identification and analysis of genomic variation across individuals has been central in biology, first through comparative genomics to answer evolutionary questions, and then in the context of ...
Guio Leiman, Laín (Date of defense: 2016-03-17)
Elucidating the fitness effects of natural genetic variants is one of the current major challenges in evolutionary biology. Understanding the interplay between genotype, phenotype and environment is ...
Soy Platero, Judit (Date of defense: 2014-07-17)
Arabidopsis thaliana seedling growth and development is influenced by both external (such as light and temperature) and internal (like hormones or circadian clock) factors. In short-day (SD) growing ...
Planas Marqués, Marc (Date of defense: 2020-10-30)
The plant pathogen Ralstonia solanacearum is the causal agent of the devastating disease known as bacterial wilt. This disease affects more than 200 plant species in over 50 families, including economically ...