Yélamos i Pena, Oriol (Date of defense: 2019-10-04)
Skin cancer is major health problem due to its increased incidence in the last decades. Standard treatment of skin cancer is still surgery, which can be challenging to perform since most skin cancers ...
Quintanilla Leo, Isabel (Date of defense: 2017-07-20)
Colorectal cancer (CRC) is one of the most frequent malignancies worldwide and it is considered an important healthcare problem. Moreover, colorectal carcinogenesis is a long stepwise process through a ...
López del Hoyo, Natalia (Date of defense: 2014-03-14)
In the last two decades, it has been done a thoroughly research about the role of Guanylate Cyclase Activating Proteins (GCAPs) in photoreceptor cells of the retina as activity regulators of Retinal ...
Costas Caudet, Laura (Date of defense: 2017-01-16)
Lymphoid neoplasms are a heterogeneous group of cancers characterized by the neoplastic or clonal proliferation of lymphoid cells in different stages of differentiation. The incidence rate of these ...
Franco Valls, Héctor (Date of defense: 2022-05-26)
SNAIL1 is a transcription factor with roles in repression of epithelial genes and enhancement of mesenchymal genes. As such, it plays a key role in Epithelial-to-mesenchymal transition and in fibroblast ...
Papageorgiou, Katherina (Date of defense: 2013-02-28)
This thesis aims to progress in deciphering the effect of the cytokines secreted by the visceral adipose tissue of obese individuals with type 2 diabetes on the endothelium, and therefore contribute to ...
Cortés Hinojosa, Marlies (Date of defense: 2017-05-26)
ZEB1 is a transcription factor whose expression in cancer cells promotes tumor initiation and progression. In this study, we for the first time characterized Zeb1 and study its function in macrophages ...
Vila Casadesús, Maria (Date of defense: 2017-09-05)
En esta tesis se han desarrollado e implementado distintas herramientas bioinformáticas que permiten el estudio de las interacciones miRNA-mRNA en contextos celulares específicos. oncretamente se ha ...
Fusté i Domínguez, Ester (Date of defense: 2012-11-19)
Resistance to antimicrobials is a well-known phenomenon leading to difficulties in the treatment of infectious diseases. The genetic determinants of such resistance are in general well understood: ...
Moreno Cabrera, José Marcos (Date of defense: 2021-06-17)
This PhD thesis has been carried out with the aim of improving, from a bioinformatic-based approach, the genetic diagnostics of hereditary cancer. More specifically, the aims were: 1. To perform a ...