Rodríguez-Vida Rodríguez, Alejo (Date of defense: 2017-10-23)
Prostate cancer is the second most frequently diagnosed cancer worldwide and the fifth leading cause of cancer death in men. Despite, the above mentioned incidence and mortality, the existence of a small ...
Roura Fornells, Esther (Date of defense: 2018-10-22)
The objective of this thesis is to estimate prospectively the association between environmental cofactors and the risk of developing cervical cancer and pre-cancer, including tobacco smoking, hormonal ...
Solé Acha, Xavier (Date of defense: 2012-03-07)
Al llarg de les dues darreres dècades hem tingut el privilegi d’assistir a un dels esdeveniments més importants en la història de la biomedicina: el desenvolupament del Projecte Genoma Humà. Conjuntament ...
Morén Núñez, Constanza (Date of defense: 2012-04-11)
It is widely known that HIV and ARV drugs trigger mitochondrial impairment in adults. However, their effects in perinatally-infected children have been poorly explored. For this reason, the main hypothesis ...
Vegliante, Maria Carmela (Date of defense: 2013-09-26)
Mantle cell lymphoma (MCL) is an aggressive subtype of non-Hodgkin lymphomas associated with poor prognosis and frequent relapses. Recently, the neuronal transcription factor SOX11 has been identified ...
Jiménez Flores, Lizbeth Minerva (Date of defense: 2018-11-09)
Gastric cancer (GC) is one of the most common types of cancer in the Western World and accounts for over 700,000 deaths every year worldwide. The prognosis is dismal, with an average 5-year survival ...
Krasheninnikova, Maria Alieva (Date of defense: 2012-11-09)
Lately adipose tissue mesenchymal stem cells (hAMSCs) have emerged as cellular vehicles for therapy of solid tumors, due to their ease of isolation and manipulation, and wound/tumor homing capacity. ...
Domenech Pena, Arnau (Date of defense: 2013-12-03)
It is estimated that within a few years chronic obstructive pulmonary disease (COPD) will be the third leading cause of death worldwide. The morbidity and mortality associated with COPD are due, in part ...
Cánovas Bilbao, Begoña (Date of defense: 2017-07-20)
In normal epithelial cells, p38α has a well-established role as a tumor suppressor. However, recent reports have illustrated pro-tumorigenic functions for the p38α pathway by promoting tumor cell survival ...
Román González, Lidia (Date of defense: 2014-01-31)
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the ...