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Mostrando ítems 9530-9549 de 41732
Design, management, and simulation of mixed station-based and free-floating vehicle-sharing systems
(English) This thesis provides tools, based on mathematical modelling, for the analysis, optimization and simulation, of vehicle-sharing systems. The thesis addresses various implementation levels of such systems, from ...
Design, Manufacture and Properties of Cr-Re Alloys for Apllication in Satellite Thrusters.
Aquesta tesi ha consistit en el disseny, fabricació i estudi de les propietats d'aleacions Cr-Re destinades a substituir els aliatges base Pt utilitzats en els motors d'apogeu i de correcció orbital de satél.lits i ha estat ...
Design, Modeling, Identification and Control of Mechatronic Systems
Les societats modernes plantegen nous reptes que demanden noves maneres de tractar els projectes d'enginyeria. Els enginyers han d'afrontar aquests reptes i desenvolupar solucions òptimes i eficients pels problemes clàssics ...
Design, monitoring and performance evaluation of high capacity optical networks
Internet traffic is expected to keep increasing exponentially due to the emergence of a vast number of innovative online services and applications. Optical networks, which are the cornerstone of the underlying Internet ...
Design, operation and control of novel electrical concepts for offshore wind power plants
Offshore wind is an emerging energy sector with a huge potential to be tapped in the near future. Offshore Wind Power Plants (OWPPs) are becoming increasingly relevant in Europe and worldwide mainly because the wind speeds ...
Design, Optimization and Characterization of Metal Oxide Nanowire Sensors
En aquesta tesi, he estudiat i desenvolupat un mètode de deposició química en fase vapor assistit per aerosol (AACVD), per al creixement directe de nanoagulles d'òxid de tungstè funcionalitzades o intrínseques. Els dipòsits ...
Design, preparation and characterization of polymer inclusion membranes as an emerging technique for preconcentration and speciation measurements
Water is essential for humankind not only for its direct consumption but also for its multiple applications in industry or agriculture, among others. The presence of undesirable substances or pollutants directly affects ...
Design, synthesis and application of supramolecular ligands in asymmetric hydrogenation and hydroformylation
En la present Tesi Doctoral s’han dissenyat i sintetitzat una família de lligands supramoleculars de tipus bis(fosfina) i una de tipus bis(fosfit) que combinen un lloc de coordinació de metalls de transició per a catàlisi ...
Design, Synthesis and Applications of V-shaped Polycarboxylate meta–Carborane-Based Metal-Organic Frameworks
Aquest treball de Tesi està dedicat a la síntesi i disseny de lligands V-shaped policarboxilat basats en la unitat meta-carborà i l’exploració de les xarxes metall-orgàniques (MOFs) d’aquests lligands amb clústers de Cu i ...
Design, synthesis and binding studies of calix(4)pyrrole based receptors suitable for ion-pair complexation and n-oxide recognition. Synthesis of resorcin(4) arene derivatives as potential ligands for supramolecular catalysis
El trabajo de tesis doctoral ha consistido en el diseño y síntesis de diferentes receptores moleculares. En particular, de nuevos derivados calix[4]pirrolaril-extendidos con dos y cuatro grupos fosfonatocomo receptores ...
Design, synthesis and biological evaluation of new polymer-drug conjugates based on polyglutamic acid and 5-Fluorouracil for the treatment of advanced colorectal cancer
Although survival rates of colorectal cancer (CRC) treated with surgery and conventional chemotherapy are high, metastatic CRC still shows acute mortality rates. Current chemotherapeutic treatment involves high doses of ...
Design, synthesis and biological evaluation of novel molecules with the capacity of inducing the degradation of different proteins by direct signaling to the proteasome
[eng] In 2001, the initial hypothesis of targeted protein degradation (TPD) was born to announce the launching of a new era of therapeutics development not by inhibiting a component of ubiquitin-proteasome system as small ...
Design, synthesis and biological evaluation of photoswitchable molecules targeting G protein-coupled receptors in retina
[eng] G protein-coupled-receptors (GPCRs) are the largest family of membrane proteins and mediate important cellular responses. Metabotropic glutamate receptors (mGlu) belong to the Glutamate family/Class C GPCR. These ...
Design, synthesis and biophysical evaluation of peptides targeting pharmacologically relevant proteins
Protein-protein interactions (PPIs) and protein surfaces are considered challenging targets for drug discovery. In this field, conventional medicinal chemistry (i.e. small molecules) has largely failed to provide effective ...
Design, synthesis and characterisation of photoswitchable allosteric modulators of metabotropic glutamate receptors
Metabotropic glutamate receptors (mGlu receptors) are class C GPCRs widely distributed through the CNS and considered pharmacological targets for neurologic disorders, such as neuropathic pain and Parkinson’s disease, ...
Design, synthesis and evaluation of the biological properties of colistin analogues
Following the laws of evolution, bacteria are capable of slowly but inexorably acquiring resistance to antibiotic compounds that we have been using for decades. Therefore, bacteria that seemed harmless to most people (such ...
Design, synthesis and study of coordination complexes for quantum computing
This thesis presents different strategies for the design of molecular complexes with the requirements to be used as two-qubit quantum gates. The approaches followed towards the preparation of potential qubit systems have ...
Design, synthesis and study of coordination complexes with spin crossover or single-molecule magnet properties
Spin crossover (SCO) complexes and single-molecule magnets (SMMs) are promising prototypes that can reach magnetic bistability within the molecular scale required for data storage. Despite the extensive library of versatile ...
Design, synthesis and study of the biological and biophysical activity of antimicrobial peptides
The global emergence and spread of multidrug-resistant bacteria is an important public health issue. However, the antimicrobial pipeline remains unacceptably lean, in fact over the last 25 years, the number of antimicrobial ...
Design, Synthesis, and Characterization of New Generation Lithium Batteries
In the last years, Li-ion batteries received great attention because of the increasing energetics requirements of modern society across a broad range of applications. We need to switch to renewable source energy and be ...
