Selective blockade of the sigma-1 receptor for the treatment of pain of different aetiology: Preclinical studies 

Gris Ormo, Georgia (Date of defense: 2015-12-04)

The present Doctoral Thesis focuses on the study of the Sigma-1 receptor (σ1R) in the field of pain. This research has been a part of the preclinical σ1R project focusing on drug discovery of σ1R ligands for the treatment ...