Ara mostrant els elements 1-7 de 7
Fernández Blanco, Álvaro (Data de defensa: 2023-04-13)
Down syndrome (DS) is the most common genetic form of intellectual disability and arises from the partial or total trisomy of the Homo Sapiens Autosome 21. The cellular and molecular mechanisms that ...
Catuara Solarz, Silvina (Data de defensa: 2016-09-16)
This Thesis aims at addressing the therapeutic potential of a neuroplasticity-targeted treatment for intellectual disability (ID) in Down syndrome (DS). The therapy consisted of the administration of ...
Sierra Noguera, Cèsar (Data de defensa: 2022-03-18)
The presence of an extra copy of Human Chromosome 21 (HSA21) in Down syndrome (DS) is one of the most complex genetic perturbations compatible with life and is the most common genetic cause of intellectual ...
Xicota Vila, Laura (Data de defensa: 2016-10-27)
Clinical trials seeking to improve cognitive performance are in dire need of biochemical biomarkers that reflect the processes taking place in the brain. In Down syndrome, this information is crucial ...
Laguna Tuset, Ariadna (Data de defensa: 2008-12-18)
El gen DYRK1A es troba situat en una regió del cromosoma 21 humà que s'ha associat a alteracions en el neurodesenvolupament. Aquest treball mostra com canvis en la dosis gènica de Dyrk1A en el ratolí ...
Alemany González, Maria (Data de defensa: 2019-07-09)
Understanding the neural correlates of intellectual disability is still a central and unresolved problem in neuroscience. Here we have unravelled several candidate neural substrates of memory impairment ...
Pons Espinal, Meritxell (Data de defensa: 2013-10-18)
Synaptic connections in the brain respond throughout their lives to the activity of incoming neurons, adjusting their biological properties to increment activity-dependent changes. Hippocampal neuronal ...