B cell ontogeny and stromal regulation of homeostatic antibody responses to commensal antigens in humans 

    Bascones Gleave, Sabrina (Fecha de defensa: 2016-12-20)

    The spleen contains a unique subset of innate-like marginal zone (MZ) B cells that rapidly mount protective antibody responses to invasive encapsulated bacteria. Here we show that human splenic MZ B cells also mount ...

    Barcelona Salut als Barris : millorant la salut en poblacions desfavorides mitjançant intervencions en salut comunitària 

    Daban Aguilar, Ferran (Fecha de defensa: 2021-04-09)

    En les últimes dècades, les desigualtats socials en salut ha estat una prioritat per la salut pública. L’any 2007 es va iniciar el programa Barcelona Salut als Barris (BSaB), una estratègia en salut comunitària per a ...

    Beat gestures and speech processing: when prosody extends to the speaker's hands 

    Biau, Emmanuel (Fecha de defensa: 2015-11-13)

    Speakers naturally accompany their speech with hand gestures and extend the auditory prosody to visual modality through rapid beat gestures that help them to structure their narrative and emphasize relevant information. ...

    Before phonemes : Infants start building the native phoneme repertoire 

    Zacharaki, Konstantina Eirini (Fecha de defensa: 2022-02-24)

    Infants start their lives with a universal ability to perceive speech and during the first months of life they attune to the language(s) they are exposed to in their environment, i.e. perceptual narrowing. Research has ...

    BeFree : a text mining system for the extraction of biomedical information from literature 

    Bravo Serrano, Àlex (Fecha de defensa: 2016-11-28)

    Current biomedical research needs to leverage the large amount of information reported in scientific publications. Automated text processing, commonly known as text mining, has become an indispensable tool to identify, ...

    Behavioral and electrophysiological correlates of cross-modal enhancement for unaware visual events 

    Pápai, Márta Szabina (Fecha de defensa: 2017-10-26)

    Diariamente recibimos mucha información que procede simultáneamente de distintos sentidos, que se combina en el cerebro para conseguir una respuesta rápida y precisa. Muchas veces, esto ocurre mediante la integración ...

    Beyond language : How linguistic input shapes attention in non-linguistic environments 

    Ayneto Gimeno, Alba (Fecha de defensa: 2016-10-18)

    Infants can live in a monolingual or a bilingual environment from birth. While being exposed to one or two language does not influence when infants achieve the main language milestones it may require different adaptations ...

    Big behavioral data analysis : computational methods for the study of continuous recordings behavior 

    Espinosa-Carrasco, José (Fecha de defensa: 2016-11-08)

    New high-throughput behavioral systems enable the recording of continuous behavioral sequences with an unprecedented richness of signals and a deep temporal resolution. Automated systems offer neuroscience the opportunity ...

    Big complexity in a minimal bacterium 

    Güell Cargol, Marc (Fecha de defensa: 2010-04-16)

    With only 689 genes Mycoplasma pneumoniae (M. pneumoniae) is among the simplest known organisms. Because of this simplicity, mycoplasma represents an attractive organism for systems-wide analyses. Such approaches aiming ...

    Bilingual insights into the initial lexicon: the role of cognates in word acquisition 

    García-Castro, Gonzalo (Fecha de defensa: 2024-03-11)

    Bilingual infants acquire words at a similar rate as monolingual ones, despite navigating a more intricate linguistic environment. The mechanisms behind this phenomenon remain elusive. Our project addressed the potential ...

    Bilingual language control : Evidence from Parkinson's disease 

    Cattaneo, Gabriele (Fecha de defensa: 2017-01-23)

    How can bilinguals easily and flexibly switch between languages without errors? The aim of this thesis is to advance our knowledge about the control mechanisms involved in bilingual language production. I investigated ...

    Biochemoinformatics: integrative computational tools at the interface between chemistry and biology 

    García Serna, Ricard (Fecha de defensa: 2010-09-27)

    The work on this thesis has focused on the development of integrated databases and visualization tools for three related areas of biomedical sciences involved in the drug discovery process. An annotated chemical library ...

    Bioinformatic analysis of epigenetic regulatory mechanisms in development and disease 

    González Ramírez, Mar (Fecha de defensa: 2021-03-19)

    Appropriate regulation of gene expression is necessary for correct development and homeostasis of organisms. Epigenetic mechanisms represent an additional layer of information, besides the genetic sequence, crucial for the ...

    Bioinformatic characterization and analysis of polymorphic inversions in the human genome 

    Martínez Fundichely, Alexander (Fecha de defensa: 2013-12-12)

    Within the great interest in the characterization of genomic structural variants (SVs) in the human genome, inversions present unique challenges and have been little studied. This thesis has developed "GRIAL", a new ...

    Bioinformatic tools for exposome data analysis : application to human molecular signatures of ultraviolet light effects 

    Hernandez-Ferrer, Carles (Fecha de defensa: 2017-11-14)

    Las enfermedades complejas se encuentran entre las más comunes y son causadas por una combinación de factores genéticos y ambientales (contaminación ambiental, estilo de vida, etc). Entre las enfermedades complejas que se ...

    Bioinformatics approaches for integration and analysis of fungal omics data oriented to knowledge discovery and diagnosis 

    Hafez Khafaga, Ahmed Ibrahem (Fecha de defensa: 2021-03-12)

    Aquesta tesi presenta una sèrie de recursos bioinformàtics desenvolupats per a donar suport en l'anàlisi de dades de NGS i altres òmics en el camp d'estudi i diagnòstic d'infeccions fúngiques. Hem dissenyat tècniques de ...

    Biological computation in yeast 

    Conde Pueyo, Núria (Fecha de defensa: 2014-09-18)

    Ongoing efforts within synthetic biology have been directed towards the building of artificial computational devices using engineered biological units as basic building blocks. Such efforts, are limited by the wiring ...

    Biological foundations of consonance perception : exploring phylogenetic roots and neural mechanisms 

    Crespo Bojorque, Paola (Fecha de defensa: 2016-12-02)

    La consonancia es una de las características más salientes de la música. A pesar de su papel fundamental en la música occidental, sus orígenes siguen siendo controversiales. Por lo tanto, la comprensión de los mecanismos ...

    Biological mechanisms in respiratory and limb muscle dysfunction in chronic respiratory conditions : influence of disease severity and body composition 

    Puig Vilanova, Ester (Fecha de defensa: 2014-07-16)

    Skeletal muscle dysfunction and wasting are major comorbidities of chronic obstructive pulmonary disease (COPD) and lung cancer (LC). Despite that the lower limb muscles are usually more severely affected, the respiratory ...

    Biomarkers and cognitive function in Down syndrome : validation for phenotyping cognitive impairment 

    Xicota Vila, Laura (Fecha de defensa: 2016-10-27)

    Clinical trials seeking to improve cognitive performance are in dire need of biochemical biomarkers that reflect the processes taking place in the brain. In Down syndrome, this information is crucial to understand the ...