Caenorhabditis elegans as animal model to investigate the cellular mechanism of resistance for the chemotherapeutic agent cisplatin 

García Rodríguez, Francisco J. (Date of defense: 2016-04-20)

In the last three decades, cisplatin has been one of the most widely prescribed drugs being an effective treatment for many cancer types. Despite its effectiveness, many patients are intrinsically resistant to cisplatin-based ...