Now showing items 1-20 of 315
Tor Roca, Alba (Date of defense: 2023-12-20)
[eng] Healthy dietary patterns, such as the Mediterranean diet, have been linked to reduced chronic disease risk and mortality. However, the evidence regarding the impact of healthy dietary patterns on physical and cognitive ...
Sortino, Rosalba (Date of defense: 2023-10-18)
[eng] G protein-coupled receptors (GPCRs) modulate diverse cellular responses to the majority of neurotransmitters and hormones within the human body. They exhibit much structural and functional diversity and are responsive ...
Murillo Villuendas, Ester (Date of defense: 2023-10-20)
[eng] Polyamines are small polycationic molecules that contain amino groups and are found in all living organisms. This study is aimed at acquiring a comprehensive understanding of the diverse roles of polyamines in plants, ...
Pérez Matas, Edgar (Date of defense: 2023-12-19)
[eng] Plant specialized metabolism is the source of a wide range of bioactive compounds, some of which with relevant pharmacological properties. Nowadays, cancer is one of the main causes of mortality worldwide, therefore, ...
Marzal Martí, Berta (Date of defense: 2023-12-18)
[spa] El cáncer de mama es el tumor más frecuentemente diagnosticado en mujeres y entre sus diversos subtipos, en esta tesis, nos centraremos particularmente en el cáncer de mama HER2+. Esta patología se caracteriza por ...
Marquès Garcia, Claudia (Date of defense: 2023-12-15)
[eng] Daphniphyllum alkaloids, isolated from various species of the Daphniphyllum genus, constitute a diverse family of natural products containing over 320 distinct members and featuring more than 20 unique polycyclic ...
Illanes Vicioso, Ramiro (Date of defense: 2023-11-10)
[spa] El desarrollo de mi tesis doctoral abarca el análisis estructural y en solución de dos proteínas mitocondriales: la isoforma 1 del Factor de Transcripción A Mitocondrial (TFAM) y el dominio N-terminal de la isoforma ...
Iannizzotto, Flavia (Date of defense: 2023-12-01)
[eng] MYC dysregulation is the most common alteration in cancers, driving several cellular processes that cooperatively promote aberrant cell growth and proliferation. Among them, the induction of protein synthesis has ...
Guercetti, Julian (Date of defense: 2023-10-25)
[eng] The current doctoral thesis titled “Microarray Strategies for Multiplexed Immunochemical Analysis” was carried out in the context of two research projects, expecting to develop multiplexed ligand-binding assays under ...
González Álamos, María (Date of defense: 2023-11-21)
[eng] The vault particle, with a mass of 10 MDa and dimensions of 70 nm x 40 nm x 40 nm, is the largest ribonucleoprotein described in the eukaryotic kingdom. The vault shell is organized in two identical moieties, each ...
Dumaze, Anaëlle (Date of defense: 2023-11-08)
[eng] My thesis was part of a collaborative project at the interface of neuropharmacology and medicinal chemistry that aimed to better understand the neuromodulation mechanisms associated with Alzheimer’s Disease (AD). In ...
Andreu March, Mònica (Date of defense: 2023-10-20)
[spa] INTRODUCCIÓN: Las estrategias de salud deben alentar a los pacientes y cuidadores a ser participantes activos de su propia atención (empoderamiento) y tomar decisiones informadas y razonadas (alfabetización en salud). ...
Alqahtani, Abdulateef (Date of defense: 2023-10-25)
[eng] In 2001, the initial hypothesis of targeted protein degradation (TPD) was born to announce the launching of a new era of therapeutics development not by inhibiting a component of ubiquitin-proteasome system as small ...
Alcalde Alvites, Miguel Angel (Date of defense: 2023-12-19)
[eng] Plant biofactories constitute an eco-friendly alternative to chemical synthesis as they have a lower environmental impact and therefore contribute to a more sustainable future. Hairy root cultures, generated by ...
Alcaide i Jiménez, Adrià (Date of defense: 2023-12-01)
[eng] Cholera is an acute life-threatening infection caused by the bacterium Vibrio cholerae, a devastating pathogen in least developed countries, which caused six world pandemics, apart from the ongoing one. Despite current ...
Alegre Martí, Andrea (Date of defense: 2023-10-04)
[eng] Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that function as biological sensors to regulate gene expression in a timeand tissue-specific and manner. The coordinated actions ...
Ballester Servera, Carme (Date of defense: 2023-10-16)
[spa] La calcificación cardiovascular (CCV) afecta a arterias y válvulas comprometiendo su normal funcionamiento y aumentando el riesgo de sufrir accidentes cardiovasculares y de desarrollar hipertrofia cardíaca e insuficiencia ...
Canadell Heredia, Ricard (Date of defense: 2023-10-06)
[spa] La epilepsia afecta a alrededor de 50 millones de personas en todo el mundo según datos ofrecidos por la Organización Mundial de la Salud (OMS). Concretamente y para tener referencia de la afectación de esta enfermedad ...
Parilli Moser, Isabella (Date of defense: 2023-09-13)
[eng] Peanuts are the most consumed nut worldwide and are widely regarded as a convenient, tasty, and easy snack that contain a variety of nutrients and bioactive compounds that are beneficial for human health. Among these ...
Pérez Calm, Adrià (Date of defense: 2023-07-28)
[eng] This thesis addresses molecular segregation in perylene-based systems, including lyotropic chromonic liquid crystals and water-in-water emulsions. These systems offer several advantages compared to conventional ...