Now showing items 47-57 of 57

    Regulación de la bioenergética mitocondrial por Mfn2 mediante los contactos RE-mitocondria y su implicación en la fisiología neuronal 

    Casellas Díaz, Sergi (Date of defense: 2021-07-01)

    Las mitofusinas 1 y 2 son unas GTPasas que se encuentran en la membrana mitocondrial externa, donde llevan a cabo el proceso de fusión mitocondrial. La existencia de mutaciones en Mfn2 es la principal causa ...

    Regulación de la expresión de PrPc como elemento clave en las modificaciones de tau en la enfermedad de Alzheimer 

    Lidón Gil, Laia (Date of defense: 2020-12-21)

    La presente tesis doctoral se inició en septiembre de 2016 como continuación del estudio ya realizado en los años previos durante el desarrollo del trabajo de fin de grado en el curso 2014- 2015 y el trabajo de fin de ...

    Regulatory mechanisms of muscle growth and metabolism in fish: modulatory by nutritional status, diet composition, exercise and muscular regeneration 

    Perelló Amorós, Miquel (Date of defense: 2021-10-20)

    With the most absolute purpose of understanding what the “simple” concept of “growth regulation” implies, the present thesis is a compilation of original works that aims to deepen in how the growth and metabolism of fish, ...

    Respuestas cardiorrespiratorias, metabólicas, mecánicas y de estrés oxidativo, agudas y crónicas, en la danza aeróbica realizada sobre una plataforma de disipación de aire en personas adultas jóvenes y mayores 

    Moreira Reis, Alessandra (Date of defense: 2023-12-15)

    [spa] INTRODUCCIÓN: La danza aeróbica (AD) es una modalidad de ejercicio de las más practicadas en el mundo que ha demostrado múltiples beneficios en la salud de aquellas personas que la practican, especialmente en la ...

    Rol d'ERK5 en la preservació de l'estabilitat genòmica i en el desenvolupament hematopoètic 

    Angulo Ibáñez, Maria (Date of defense: 2016-09-09)

    Una provisió adequada de nucleòtids és essencial per una replicació acurada del DNA, i concentracions inapropiades de dNTPs poden conduir a situacions d’estrès de replicació, una font de dany al DNA, inestabilitat genòmica ...

    Role of CLA+T lymphocytes in the mechanisms triggering psoriasis 

    Jesús Gil, Carmen de (Date of defense: 2021-06-01)

    Psoriasis is a common immune-mediated inflammatory skin condition affecting around 2% of the population worldwide. Different disease subtypes have been described regarding their specific clinical phenotype: chronic plaques, ...

    Secretory and synaptic proteins in brain and cerebrospinal fluid in normal and Alzheimer’s disease animal models 

    Sánchez Domínguez, Irene (Date of defense: 2022-11-25)

    [eng] The central nervous system represents a huge network architecture where intercellular communication governs and coordinates the proper function of the brain. Regulated secretion of neuropeptides and growth factors ...

    Selective effects of Liver X Receptor activation in host-bacteria interaction 

    Glaría Percaz, Estibaliz (Date of defense: 2021-06-16)

    Macrophages exert potent microbicidal functions against pathogens; however, some intracellular bacteria have developed strategies to survive within intracellular phagolysosomes and use macrophages as a preferential niche ...

    Skeletal muscle and cardiac adaptations to swimming-induced exercise in adult zebrafish = Adaptacions del múscul esquelètic i cardiac a l'exercici per natació induïda en el peix zebra adult 

    Rovira i Berger, Mireia (Date of defense: 2016-11-14)

    In mammals, regular exercise is related to important benefits for health by protecting from the development of cardiovascular diseases, stimulating the immune system by providing anti- inflammatory effects and maintaining ...

    The role of CLA+T lymphocytes in the development of Atopic Dermatitis 

    Sans de San Nicolàs, Lídia (Date of defense: 2023-10-26)

    [eng] Atopic dermatitis is the most common chronic immune-mediated inflammatory skin disease affecting up to 20% of children and 10% of adults. The complex pathophysiology of the disease comprises genetic susceptibility, ...

    WT1 in heart and gonad development: a crucial gene for cell plasticity and differentiation 

    Torres Cano, Alejo (Date of defense: 2021-04-30)

    Wt1 is a complex gene that encodes a protein whose best described function is to act as a transcription factor. Wt1 plays a crucial role in several organ developments, including kidneys, liver, heart or gonads. Moreover, ...