Now showing items 38-57 of 85

    Ligandos Supramoleculares en Complejos Metálicos con Propiedades Físicas Relevantes 

    Maxwell Villacorta, Lindley Andrés (Date of defense: 2017-06-16)

    En la primera parte de esta tesis, se basó en la síntesis de ligandos basados en la heptazina y los complejos formados con CuII. Utilizando 2-dipiridilamina para funcionalizar el núcleo de heptazina, (ligando que presenta ...

    Luminescent gold(I) supramolecular assemblies on materials and biological chemistry 

    Pinto Martínez, Andrea (Date of defense: 2021-11-05)

    During the last years, the research group where this Doctoral Thesis has been carried out has been pioneer in the development of different gold(I) complexes and resulting supramolecular assemblages with a wide variety of ...

    Materiales piezoeléctricos derivados del (Bi0,5Na0,5)TiO3-BaTiO3 : preparación y estudio de las propiedades funcionales 

    Cerdeiras Montero, Elena (Date of defense: 2016-11-17)

    Los materiales piezoeléctricos basados en el titanato zirconato de plomo (PZT) son ampliamente utilizados en una gran cantidad de dispositivos electrónicos debido a sus excelentes propiedades eléctricas. Esta mejora de las ...

    Mechanistic insights into substrate-assisted catalysis in glycosidases by means of QM/MM molecular dynamics 

    Coines Lopez-Nieto, Juan (Date of defense: 2021-01-20)

    Carbohydrates are essential molecules in biotechnology and for the proper functioning of living organisms. They are involved in energy storage, being structural components or participating in crucial biological processes ...

    Molecular-based Magnetoresistance Devices at Room Temperature 

    Martín Rodríguez, Alejandro (Date of defense: 2021-09-15)

    In this doctoral thesis a series of computational and experimental studies of molecular magnetoresistance devices at room temperature is presented. This sort of devices is included in the molecular electronics framework ...

    Multisensitive polyurethane/polyurea nanocapsules for smart drug delivery 

    Cuscó Marigó, Cristina (Date of defense: 2018-03-22)

    The Thesis is based on the development of a potentially-scalable methodology to prepare polyurethane/polyurea polymers to nanoencapsulate bioactive molecules. In the first part of the project, the design, optimization and ...

    New Catalytic Methods for Pauson-Khand Reactions, Isomerization and Asymmetric Hydrogenations. Application to the Synthesis of Bioactive Compounds 

    Cabré Montesinos, Albert (Date of defense: 2020-01-31)

    The main contribution of this doctoral thesis has been devoted to the field of synthetic organic chemistry. The Pauson-Khand reaction (PKR) is a metal-catalyzed [2+2+1] cycloaddition between an alkyne, an alkene and a ...

    New organic semiconductors based on the carbazole core: synthesis and application in optoelectronic devices 

    Bujaldón Carbó, Roger (Date of defense: 2022-11-22)

    [eng] The increasing demand on next-generation displays encourages an exhaustive research on the development of new and enhanced semiconductors. Apart from the conventional inorganic materials, organic-based semiconductors ...

    Ni-based catalysts for H2 production from ethanol steam reforming: Effect of the support and use of CO2 as regenerating agent and reactant 

    Bednarczuk, Lukasz (Date of defense: 2017-01-11)

    In this work, the effect of CO2 on the hydrogen production under substoichiometric ethanol steam reforming (ESR) conditions over nickel based catalysts was studied. A special emphasis was focused on the application of ...

    Nova síntesi d'interès industrial d'un fàrmac genèric 

    Tolrà Rovira, Roser (Date of defense: 2017-07-21)

    L'objectiu principal d'aquesta Tesi doctoral ha estat l’obtenció d’una via alternativa a les existents per a l'obtenció d'un intermedi clau, 1, en la síntesi d'un fàrmac anticoagulant. La nova via havia de ser novedosa i ...

    Novel antimicrobial peptides for therapeutic applications: design, synthesis, characterization, and evaluation of their biological and biophysical activity 

    Segovia Laserna, Rosario (Date of defense: 2022-03-08)

    After decades of exorbitant antibiotic misuse and overuse in human medicine, agriculture and livestock industry, multidrug resistant bacteria (MDR) have become a major medical concern. In this regard, the design of new, ...

    Novel chemical tools for Cancer therapy and imaging: from targeted photoactivatable Pt(IV) complexes to coumarin-based fluorophores and caging groups 

    Gandioso Ubieto, Albert (Date of defense: 2018-11-12)

    In the present Thesis, it has been carried out the development of new chemical tools for the diagnosis and treatment of cancer through the use of light as an external factor. On the one hand, light can be used to control, ...

    Novel methodologies for the conjugation and cyclisation of polyamides 

    Brun Cubero, Omar (Date of defense: 2016-07-27)

    An alternative allowing diene-derivatised polyamides to be used in Diels-Alder conjugation reactions has been explored and developed. In this methodology, conjugation takes place between a fully protected, resin-linked ...

    A novel regulatory unit in the N-terminal region of c-Src 

    Arbesú Andrés, Miguel (Date of defense: 2018-03-02)

    c-Src is a central player in several cellular signaling pathways. It controls impor- tant cellular processes like cellular proliferation, survival or motility. Therefore, a number of tumoral diseases have been related to ...

    Nuevos materiales macromoleculares formados por la unión de moléculas con estado birradical triplete asequible térmicamente 

    San Juan Ocete, Alexis (Date of defense: 2018-07-13)

    Estudios previos de nuestro grupo de investigación describieron moléculas orgánicas heterocíclicas, aparentemente de capas cerradas que presentan carácter birradical triplete asequible térmicamente. La formación de esta ...

    Oligopeptides as highly versatile agents against copper-mediated oxidative stress and amyloid-β aggregation 

    Vázquez Bigas, Guillem (Date of defense: 2019-03-22)

    Alzheimer’s disease (AD), for which no cure is known yet, is currently the most prevalent cause of dementia for the elderly population. The aberrant aggregation of β-amyloid peptide (Aβ) is believed to trigger the events ...

    Optimización de etapas claves en la síntesis de Palmerolidas. Síntesis de la Palmerolida 

    Arribas Crovara, Maria Fernanda (Date of defense: 2022-11-11)

    [spa] En el primer bloque de la tesis describimos nuestra aproximación a la síntesis total de la Palmerolida D, un compuesto de gran interés, tanto por sus propiedades antitumorales como por la diversidad de reacciones ...

    Organocatálisis asimétrica. Desarrollo de catalizadores y estudio de los mecanismos implicados 

    Carneros García, Héctor (Date of defense: 2018-06-29)

    El desarrollo de métodos para la creación de nuevos enlaces carbono-carbono de forma sostenible y selectiva es clave en la química orgánica actual. En las últimas décadas, ha aumentado de gran manera el interés en llevar ...

    Organocatálisis y transferencia de quiralidad mediante porfirinas autoensamblantes solubles en agua 

    Arlegui Chamizo, Aitor (Date of defense: 2019-12-16)

    La quiralidad es una propiedad fundamental de la naturaleza. La vida en la Tierra se basa en la quiralidad. Casi todos los compuestos quirales presentes en los organismos vivos se encuentran solo en una de sus formas ...

    P-Stereogenic Intermediates and MaxPHOX ligands. Iridium Catalyzed Asymmetric Hydrogenations 

    Salomó i Prat, Ernest (Date of defense: 2018-10-19)

    Asymmetric hydrogenation of double bonds by means of organometallic catalysis is a powerful tool for organic synthesis; it is an efficient and simple method to produce valued chiral compounds. Among the many different ...