Mostrando ítems 1-6 de 6
Magallón Lorenz, Miriam (Fecha de defensa: 2023-07-07)
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with ...
Bujosa Rodriguez, Paula (Fecha de defensa: 2023-09-27)
[eng] Linker histones are essential proteins involved in higher-order chromatin structures and architectural functions. However, their roles extend beyond structure, encompassing various chromatin ...
Sánchez Baizán, Núria (Fecha de defensa: 2023-10-27)
[eng] Epigenetic mechanisms play a vital role in gene expression regulation and phenotype determination. This thesis aimed to comprehensively investigate the transcriptome, the methylome and the influence ...
Molina Jordán, Marc (Fecha de defensa: 2023-12-04)
[eng] The application of mechanical force to the nucleus has been recently shown to regulate important functions, including nucleocytoplasmic transport (NCT), chromatin organization, and gene expression. ...
Xiol Viñas, Clara (Fecha de defensa: 2023-12-22)
[eng] Rett syndrome (RTT) is a severe neurodevelopmental disorder characterized by a regression in acquired skills, such as purposeful hand use and language, after an apparently normal early development. ...
Salvadores Ferreiro, Marina (Fecha de defensa: 2024-01-18)
[eng] Mutations exhibit an uneven distribution across the human genome, with a regional mutation density (RMD) influenced by chromatin landscapes and replication timing. While there is a good understanding ...