Matas Gironella, Júlia (Date of defense: 2021-12-20)
Colorectal cancer (CRC) is a major health burden with large numbers of new cases worldwide and high disease-specific mortality, despite great advances made towards improving patient clinical outcomes. ...
Serra Vinardell, Jenny (Date of defense: 2015-09-18)
La malaltia de Gaucher (GD) forma part d'un conjunt de malalties que es coneixen amb el nom de "malalties d'acumulació lisosómica". La GD n'és la més prevalent i en la majoria de casos és causada per ...
Arroyo Sánchez, Rodrigo (Date of defense: 2014-06-20)
Network and systems biology disciplines could revolutionize the study of complex diseases by taking proteins back to their context, considering a much broader perspective of their environment without ...
Gonzàlez Juncà, Alba (Date of defense: 2013-11-15)
The TGF-beta oncogenic effect has been widely studied. In glioma, TGF-beta has an oncogenic role increasing cell proliferation and glioma-initiating cell (GIC) self-renewal capacity. During the investigation ...
Bellmunt i Tarragó, Anna (Date of defense: 2017-12-15)
The identification of genes that mediate metastasis is pivotal to better understand the mechanism, to develop novel drugs and to stratify patients with highest risk and consecutively administrate them ...
Cuesta Borràs, Estefania (Date of defense: 2019-11-28)
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. ...
Arenas Lahuerta, Enrique Javier (Date of defense: 2017-04-07)
Breast Cancer (BC) is one of the major causes of cancer deaths in women. BC is a heterogeneous disease, and within the heterogeneity of the tumor, Tumor-Initiating Cells (TICs) have been reported as ...
Sánchez-Cid Pérez, Lourdes (Date of defense: 2017-02-15)
Esta tesis consiste en el estudio de la regulación por microRNAs del proceso de metástasis de carcinomas ductales invasivos de mama. Hemos encontrado una expresión alterada de varios microRNAs en muestras ...
Silva, Rui Gonçalo Teixeira da (Date of defense: 2022-09-16)
Steatotic livers are considerably more prone to IRI, in which turn, it is known to impair mitochondrial function. Our working hypothesis lies on the fact that impaired mitochondrial function and reduced ...
Cañellas Socias, Adrià (Date of defense: 2022-07-22)
Colorectal cancer (CRC) kills around 700,000 people worldwide every year. The majority of these deaths are the result of dissemination of the disease to foreign organs. Despite undergoing curative ...