Browsing Facultat de Biologia by Subject "576"

Now showing items 1-5 of 5

    Analysis of the contribution of Barrier-to-Autointegration Factor (BAF) to centromere function and mitosis progression 

    Escudero Ferruz, Paula (Date of defense: 2021-06-28)

    This work is focused on Barrier-to-Autointegration Factor (BAF) protein. BAF is a nuclear envelope (NE) component that binds chromatin and is required for NE reassembly (NER) at mitosis exit. Previous work in our group ...

    Mechanisms that regulate intracellular DNA entanglement 

    Dyson Coral, Silvia (Date of defense: 2021-12-14)

    Topoisomerase II often produces DNA knots and catenates when its DNA strand passage activity equilibrates the topology of intracellular DNA. However, these DNA entanglements are detrimental for the normal development of ...

    Network biology identifies novel apoptosis-related proteins and synergistic drug combinations in breast cancer 

    Capdevila Busquets, Eva (Date of defense: 2016-03-17)

    Breast cancer is a very heterogeneous disease with a poor prognostic outcome, largely due to its resistance to current cancer therapies. The balance between cell proliferation and apoptosis plays a critical role in determining ...

    Programas de splicing y desarrollo neuronal: función de la quinasa KIS 

    Moreno Aguilera, Marcos (Date of defense: 2023-09-29)

    [spa] El splicing alternativo es un proceso que además de proporcionar diversidad al transcriptoma y proteoma celular, añade una nueva capa de regulación en la expresión de proteínas y en la función que estas desempeñan. ...

    SLIMP: a mitochondrial protein involved in cell cycle regulation 

    Pons Pons, Alba (Date of defense: 2021-12-16)

    SLIMP (Seryl-tRNA Synthetase-Like Insect Mitochondrial Protein) was identified during the generation of a mitochondrial human disease fly model. SLIMP was described as a previously uncharacterized paralog of the Drosophila ...