Prieto Barja, Pablo (Date of defense: 2017-01-12)
In this PhD I have used NGS technologies in different organisms and scenarios such as in ENCODE, comparing the conservation and evolution of long non-coding RNA sequences between human and mouse, using ...
Balart i García, Pau (Date of defense: 2023-02-24)
Under very specific pressures, evolution turns extremely convergent, to the extent that distantly-related organisms show highly similar morphological, physiological and behavioral adaptations. Life into ...
Plass Pórtulas, Mireya (Date of defense: 2011-07-12)
L’splicing és el mecanisme pel qual els introns són eliminats del pre-mRNA per generar un trànscrit madur. Aquest procés és dut a terme per un complex macromolecular anomenat spliceosoma i requereix el ...
López Valenzuela, María (Date of defense: 2015-01-15)
MicroRNAs (miRNAs) are major contributors to phenotypic diversity and have a demonstrated role in evolution. We performed an analysis on how miRNA nucleotide substitutions may have contributed to human ...
Heredia Genestar, José María (Date of defense: 2020-01-28)
La mutació és un procés essencial per l’evolució, tot i que també té un rol important tant en el càncer com en altres malalties. Les mutacions no s’acumulen uniformement al llarg del genoma i la seva ...
Jiménez Asins, Alba (Date of defense: 2016-05-11)
Per tal d'estudiar la relació complexa entre l'estructura d'un circuit genètic i la seva funció, ens centrem en estudiar dues proprietas: la seva capacitat evolutiva i la seva multi-functionalitat. ...
Renom, Pere (Date of defense: 2023-02-22)
According to estimates, over the 3.5 billion years that have elapsed since the appearance of life, the Earth has been inhabited by some 4 billion different species, of which 99.99% have already become ...
Elek, Anamaria (Date of defense: 2024-04-19)
Single-cell genomics methods have revolutionized the study of gene expression and regulation at the cell type level. Generating single-cell atlases for species at key phylogenetic positions of the animal ...