Facultat de Química: Recent submissions
Now showing items 81-100 of 130
Drogas y psicofármacos: estudio de su presencia en el medio ambiente (aguas residuales, sedimentos y mejillones) y evaluación de su consumo e impacto
En esta tesis doctoral se han desarrollado tres metodologías analíticas para el análisis de drogas, psicofármacos y sus metabolitos en tres compartimentos medioambientales: aguas residuales, sedimentos y biota. Las ...
Conformational catalytic itineraries of five- and six-membered sugar rings in enzymatic and superacid media
Carbohydrates were early considered important for energy storage and structural support for living organisms. It was not until a few decades ago that scientist discovered that they are also involved in much more complex ...
Development and applications of photoswitchable muscarinic ligands
Modern medical treatments are largely based on the ability of pharmacological drugs to interact with a molecular target in the human body (e.g., receptors) in order to evoke a physiological response. Such targets are ...
Chemical and ecotoxicological assessment of microplastics and emerging risks in the coastal environments
In recent decades, global plastics production and consumption have continued to increase. Although many policy strategies on waste prevention and recycling have been implemented, much of the plastic waste is dispersed in ...
Contaminants organoclorats, organobromats i organofosforats en població general
Durant les dècades dels anys 50 i 60 del segle XX es van utilitzar arreu del món diferents tipus de compostos organoclorats i organobromats, que pertanyen als contaminants orgànics persistents (COPs), com a pesticides, ...
An integrated assessment of nanoparticle exposures in the ceramic industry
Exposure to nanoparticles has been associated with adverse effects on human health. When the exposure route is inhalation, nanoparticles can cause pulmonary inflammation which may be more severe than from fine particles, ...
Organic pollutants in indoor dust: method development, site-specific monitoring and human exposure
Dust has been used as a surrogate of indoor organic contamination for several decades. Their concerns for human health include from sensitization effects such as allergies to toxic effects derived from those organic ...
L'alcohol terc-butílic com a solvent d'interés analític: equilibris protolítics i les seves aplicacions
L’objecte primordial del present treball ha estat l’estudi teòric i pràctic d’un solvent, l’alcohol terc-butílic, que tot i essent un dels solvents més semblants a l’aigua, presenta respecte a ella notables diferències. ...
Desarrollo y caracterización del efecto doble memoria de forma obtenido mediante martensita estabilizada en aleaciones base cobre y de la fenomenología de envejecimiento
Se han obtenido distintas aleaciones policristalinas de base cobre así como monocristalinas de ZuCnAlCo, las cuales han sido caracterizadas quimícamente, estructural y calorimétricamente. Se ha utilizado un nuevo método ...
Structural characterization of amyloid beta oligomers with functional links associated to Alzheimer's disease
Alzheimer’s disease (AD) is the most common form of dementia. It was first described in 1906 by Alois Alzheimer. Later on, in 1984 George Glenner and Colin Masters isolated the amyloid-beta (Aβ) peptide from a human brain ...
Deposition of environmentally friendly cermets coatings by thermal spray techniques
The main objective of this research work was to produce environmentally friendly cermets coatings, Ni and Co free matrix, alternative to conventional WC- Co, by thermal spray processes. WC-Co cermets has always been one ...
Simulación de una columna de paredes mojadas como reactor de sulfonación
Este trabajo se ha concebido como continuación de otros anteriores, realizados en el Departamento de Química Técnica de la Facultad de Química de la Universidad de Barcelona, sobre sulfonación con SO(3) vapor en reactor ...
Utilització de 9-fluorenilmetoxicarbonilaminoàcids a la síntesi en fase sòlida de segments peptídics protegits
L'objectiu principal d'aquesta Tesi és posar a punt una metodologia de síntesi en fase sòlida de segments peptídics protegits, la qual cosa comporta l´engalzament successiu dels aminoàcids sobre el suport sòlid, el ...
3d and/or 4f coordination compounds derived from chiral Schiff bases: magnetic and spectroscopic study
This PhD thesis has been developed in the Molecular Magnetism Group of the University of Barcelona. As its name indicates, the Molecular Magnetism Group is mostly interested in the magnetic study of coordination complexes, ...
Information Transfer and Dynamics of Nucleic Acids studied by Theoretical Approaches
1. The Force Field Accuracy Problem. The utility and applicability of MD simulations to model biomolecular systems goes only as far as its ability to sufficiently sample the conformational space and the correct description ...
Non-glycosidic analogues of alpha-galactosylceramide: Design, synthesis and biological activity
The Immune System (IS) is a complex collection of tissues, organs, cells and molecules to defense the body against threatens. IS is organized into two lines of defense: innate immunity which acts in a non-specific manner ...
Development and application of Nuclear Magnetic Resonance spectroscopy and chemometric methods for the analysis of the metabolome of Saccharomyces cerevisiae under different growing conditions
Nuclear Magnetic Resonance (NMR) spectroscopy is able to produce by a single direct measurement a very high amount of chemical information. However, this information is not always easy to interpret. In fact, the complexity ...
Towards the validation of a druggable amyloid-beta oligomer as a target for Alzheimer´s disease = Cap a la validació d’un oligomer de beta-amiloide com a diana en la malaltia d’Alzheimer
Amyloid-beta peptide (Aβ) is strongly linked to the aetiology of Alzheimer’s disease (AD). Aβ is the main component of the amyloid plaques found in the brain of AD patients, however, Aβ is also present in the brain of ...
Synthesis of Sonic Hedgehog protein and development of peptide binders using phage display libraries
Chemical protein synthesis has become a potent tool for the synthesis of proteins, especially those which are not easily accessed by DNA recombinant methods, such as proteins with posttranslational modifications. The key ...
Assessment of the lipidomic effects of environmental pollutants on exposed organisms using chemometric and analytical methods
Lipidomics is a subset of metabolomics, which in turn, is one of the categorical platforms that constitute omics. Omic sciences aim at the study of the abundance and (or) structural characterization of a broad range of ...
