Ara mostrant els elements 1-10 de 23
Rosselló Tortella, Margalida (Data de defensa: 2021-12-09)
Transfer RNAs (tRNAs) are essential molecules that allow the translation of the genetic code into amino acids. Extensive research during the last 50 years have revealed that, despite their apparently ...
Solé Acha, Xavier (Data de defensa: 2012-03-07)
Al llarg de les dues darreres dècades hem tingut el privilegi d’assistir a un dels esdeveniments més importants en la història de la biomedicina: el desenvolupament del Projecte Genoma Humà. Conjuntament ...
Jiménez Flores, Lizbeth Minerva (Data de defensa: 2018-11-09)
Gastric cancer (GC) is one of the most common types of cancer in the Western World and accounts for over 700,000 deaths every year worldwide. The prognosis is dismal, with an average 5-year survival ...
Pérez Salvia, Montserrat (Data de defensa: 2019-03-01)
Cancer is considered nowadays a genetic and epigenetic disease. Aberrancies in epigenetic marks in DNA and histone tails together with alterations in epigenetic regulators responsible of catalyzing ...
Celià Terrassa, Antoni (Data de defensa: 2012-05-14)
This Doctoral Thesis project is part of a broader research program whose global aim is to better understand key molecular and cellular events in tumor metastasis, in particular those associated with ...
Royo Garrido, Romina (Data de defensa: 2023-03-31)
[eng] Next-generation sequencing (NGS) has revolutionized biomedical sciences, especially in the area of cancer. It has nourished genomic research with extensive collections of sequenced genomes that ...
Moreno Càceres, Joaquim (Data de defensa: 2016-01-18)
The transforming growth factor-beta (TGF-β) is a cytokine involved in many physiological and pathological processes. Its dual role has been described in the liver, where it can either induce pro- or ...
Oliveira Mateos, Cristina (Data de defensa: 2020-06-16)
The vast majority of the human genome is transcribed giving rise to non-coding RNAs. Antisense transcripts are one of the most abundant types of long non-coding RNAs and many of them have regulatory ...
Bellmunt i Tarragó, Anna (Data de defensa: 2017-12-15)
The identification of genes that mediate metastasis is pivotal to better understand the mechanism, to develop novel drugs and to stratify patients with highest risk and consecutively administrate them ...
Rofes Terrón, Paula (Data de defensa: 2022-03-31)
The overarching aim of the present thesis project is to implement new testing strategies and develop new tools that will contribute to improve the genetic diagnosis of hereditary cancer, with the ultimate ...