Vallverdú Ginès, Júlia (Date of defense: 2021-10-20)
La tesi doctoral es centra en la generació i caracterització de les cèl·lules estrellades hepàtiques derivades de cèl·lules mare pluripotents induïdes (iPSCs), anomenades com iPSC-HSCs, pel modelatge ...
Balmori de la Puente, Alfonso (Date of defense: 2020-10-23)
Phylogenetic and phylogeographic methods allow studying the evolutionary relationships between populations and species, patterns of genetic structure, and historical events that have modelled the current ...
Atla, Goutham (Date of defense: 2021-05-05)
Diabetes mellitus is a heterogeneous group of metabolic diseases characterized by impaired blood glucose homeostasis that affects more than 415 million people worldwide and is a leading cause of mortality. ...
Iacobucci, Simona (Date of defense: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural ...
Gaspar Torrubia, Ana Elena (Date of defense: 2021-11-30)
El modelo tumoral presentado por nuestro laboratorio ha demostrado que los tumores CIN son capaces de reproducir de forma eficiente fenómenos invasivos de los tumores epiteliales. De acuerdo con los ...
Ugarteburu López, Olatz (Date of defense: 2021-09-30)
Las enfermedades del metabolismo energético mitocondrial son un grupo de patologías con una gran heterogeneidad clínica, bioquímica y genética. Aunque en la última década la implementación de las técnicas ...
Ferrández Roldán, Alfonso (Date of defense: 2021-02-22)
The bloom of genomic data has revealed a vast amount of gene losses across all life kingdoms. However, the impact of gene loss on the evolution of the mechanisms of embryo development remains an important ...
Guberović, Iva (Date of defense: 2021-10-01)
The histone variant macroH2A is the only structural chromatin component containing a macrodomain. In vertebrates, two genes and one event of alternative splicing give rise to three macroH2A proteins ...
Blanco Ameijeiras, Jose Manuel (Date of defense: 2023-03-24)
[eng] The Central nervous system (CNS) originates from the coordinated events that result into neural specification and the morphogenic events that shape the neural tube (NT). Then, the embryonic NT ...
Garcia Mayea, Yoelsis (Date of defense: 2020-12-11)
Head and neck squamous cell carcinoma (HNSCC) is usually diagnosed in advanced stages. The treatment has not changed much on the last decades, being limited to surgery followed by radiotherapy and/or ...