Ara mostrant els elements 1-9 de 9
Camacho Castillo, Luz del Carmen (Data de defensa: 2011-03-31)
Cer and So are involved in regulation of apoptosis and cell cycle arrest while on the other hand S1P promotes cell growth and inhibits apoptosis. The antagonistic effects of these metabolites are regulated ...
Coll San Martín, Laia (Data de defensa: 2021-11-29)
Cancer was reported as the second leading cause of death in 2018 by the World Health Organisation. Cancer is defined as the set of diseases that proceeds in multiple phases generating a transformation ...
Magallón Lorenz, Miriam (Data de defensa: 2023-07-07)
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with ...
Martorell Aleman, Òscar (Data de defensa: 2014-03-25)
During last decades many researchers have tried to elucidate the different causes of tumour initiation and progression. For this purpose, multiple animal models have been developed to understand the ...
Moles Fernández, Alejandro (Data de defensa: 2022-01-31)
Patients with hereditary breast and ovarian cancer (HBOC) in whom a causative pathogenic variant is not identified after genetic analysis may not benefit from prevention, early detection, or precision ...
Mazuelas Gallego, Helena (Data de defensa: 2021-01-28)
Neurofibromatosis type 1 (NF1) is a genetic disease caused by inherited mutations in the NF1 gene. NF1 is a cancer predisposition syndrome, and the disease’s hallmark is the appearance of tumors of the ...
Díaz Gay, Marcos (Data de defensa: 2019-11-25)
Colorectal cancer (CRC) is one of the malignant neoplasms with higher incidence and mortality in Spain, Europe and worldwide. As a complex disease, both environmental and genetic factors influence CRC ...
Mas-Ponte, David (Data de defensa: 2022-11-14)
[eng] Somatic cells accumulate mutations in their genome from a set of exogenous and endogenous processes. The interplay of DNA lesions and the DNA repair mechanisms in each cell shape the genetic ...
Salvadores Ferreiro, Marina (Data de defensa: 2024-01-18)
[eng] Mutations exhibit an uneven distribution across the human genome, with a regional mutation density (RMD) influenced by chromatin landscapes and replication timing. While there is a good understanding ...