Mostrando ítems 31-40 de 60
Magallón Lorenz, Miriam (Fecha de defensa: 2023-07-07)
[eng] Malignant peripheral nerve sheath tumors (MPNSTs) are rare soft-tissues sarcomas of the peripheral nervous system (PNS) with poor prognosis and lack of therapeutic options. Complete resection with ...
Salinas Pena, Mónica (Fecha de defensa: 2023-09-20)
[eng] The histone H1 family comprises up to seven members in human somatic cells. However, H1 studies have been limited by the lack of specific ChIP-grade antibodies. Here, we have mapped six endogenous ...
Clua Villas, Anna (Fecha de defensa: 2023-07-17)
[eng] G-quadruplexes are non-canonical DNA structures that appear in Guanine-rich oligonucleotides. Four Guanines interact through Hoogsteen hydrogen bonds forming a tetrad which is stabilized by metallic ...
Raimondi, Giulia (Fecha de defensa: 2020-06-08)
The general goal of this thesis has been to progress oncolytic adenovirus therapy for PDAC, by the incorporation of novel preclinical models to test for patient-specific responses and the generation of ...
Fernández Alfara, Marcos (Fecha de defensa: 2022-04-07)
Translation of mRNAs into proteins is a highly regulated step of gene expression. In cancer, post-transcriptional and translational control have a critical effect on transformation, controlling ...
Acevedo Lipes, Andrea Milena (Fecha de defensa: 2021-03-09)
Clinical pathologists identify visually many morphological features to characterize the different normal cells, as well as the abnormal cell types whose presence in peripheral blood is the evidence of ...
Franco Valls, Héctor (Fecha de defensa: 2022-05-26)
SNAIL1 is a transcription factor with roles in repression of epithelial genes and enhancement of mesenchymal genes. As such, it plays a key role in Epithelial-to-mesenchymal transition and in fibroblast ...
Moreno Cabrera, José Marcos (Fecha de defensa: 2021-06-17)
This PhD thesis has been carried out with the aim of improving, from a bioinformatic-based approach, the genetic diagnostics of hereditary cancer. More specifically, the aims were: 1. To perform a ...
Aubets Gil, Eva (Fecha de defensa: 2021-09-19)
This work is focused on the study of Polypurine Reverse Hoogsteen hairpins (PPRHs) as a gene silencing tool, and on the search of alternative methods for their delivery, including viral and non-viral ...
Moles Fernández, Alejandro (Fecha de defensa: 2022-01-31)
Patients with hereditary breast and ovarian cancer (HBOC) in whom a causative pathogenic variant is not identified after genetic analysis may not benefit from prevention, early detection, or precision ...
616 - Patología. Medicina clínica. Oncología (30)
577 - Bioquímica. Biología molecular. Biofísica (13)
575 - Genética general. Citogenética general. Inmunogenética. Evolución. Filogenia (6)
615 - Farmacología. Terapéutica. Toxicología. Radiología (2)
663/664 - Alimentos y nutrición. Enología. Aceites. Grasas (2)