Ruiz Cánovas, Eugenia (Date of defense: 2018-12-10)
Compound F has been reported to possess important antioxidant, anti-inflammatory, anti- diabetic and anti-cancer effects, among other interesting properties. Although Compound F has been extensively ...
Henryka Gawrzak, Sylwia (Date of defense: 2016-11-23)
Breast cancer is the most frequently diagnosed cancer and remains the second leading cause of death among women in Europe and United States. In this malignancy, metastasis remains to be an incurable ...
López Fauqued, Marta (Date of defense: 2010-06-22)
Malignant melanoma is the most lethal skin cancer with no effective therapeutic treatment in its metastatic stages. RAS and PI3K pathways have been shown to play a critical role in melanoma development ...
Nieves Calatrava, Ingrid (Date of defense: 2015-11-24)
One of the ultimate goals in biomedicine is to understand the relationship between structure, function, and dynamics of biomolecules in living cells. The biophysical tools designed to gain more insight ...
Styrczewska, Katarzyna (Date of defense: 2017-09-22)
Voltage-gated K channels (Kv) is large family of channels that are expressed in both excitable and non-excitable cells. In excitable cells they contribute to the control of resting membrane potential ...
Valls Margarit, Maria (Date of defense: 2017-07-07)
Ischemic heart disease is a major cause of human death worldwide owing to the heart minimal ability to repair following injury. Other than heart transplantation, there are currently no effective or ...
Sabbaghi Mehrjardi, Mohammad Ali (Date of defense: 2017-09-19)
Trastuzumab-emtansine (T-DM1) is an antibody-cytotoxic agent (DM1) conjugated drug. DM1 delivery by trastuzumab inside the HER2 positive cells affects microtubule polymerization, cell cycle arrest and ...
Guillén Boixet, Jordina (Date of defense: 2015-12-04)
Cytoplasmic polyadenylation element binding proteins (CPEBs) are a family of RNA-binding proteins essential for the translational regulation of mRNAs in various biological contexts. CPEBs recognize CPE ...
Amara, Imen (Date of defense: 2012-07-12)
In order to improve our understanding on LEA proteins and their molecular functions in drought tolerance, the present work analyzes in the first place, the composition of LEA subproteomes from Arabidopsis ...
Rodríguez Carbó, Laia (Date of defense: 2016-01-25)
The androgen receptor (AR) is a ligand-activated transcription factor that plays a crucial role in the correct development, differentiation, and function of male reproductive organs. Alterations in the ...