Aledavood, Elnaz (Date of defense: 2021-10-01)
This doctoral thesis is focused on disclosing molecular factors that regulate the functional mechanism of key targets in i) metabolic disorders, such as diabetes and obesity, and ii) tuberculosis (TB). ...
Panarello, Silvia (Date of defense: 2021-12-15)
Photopharmacology has the main purpose to allow the control of protein activity with light. The most exploited strategy used to achieve this objective is the freely diffusible photopharmacology and it ...
Villamor Payà, Marina (Date of defense: 2021-07-08)
The Tousled like kinases 1 and 2 (TLK1 and TLK2) are evolutionarily conserved Ser/Thr kinases that are required for genome stability and normal development in numerous organisms. Both kinases contribute ...
Meer, Golda Van der (Date of defense: 2021-04-13)
Cuando la naturalidad del territorio ha desaparecido, solo en el poema puede una lengua minoritaria luchar por subsistir. Esta tesis examina cómo los factores históricos pueden modificar la relación con ...
Iacobucci, Simona (Date of defense: 2021-03-18)
Taking into consideration the current knowledge about the subjects treated, several goals were proposed for this PhD thesis in order to further understand PHF8 function in both astrocytes and neural ...
Ortega Tañá, Laura (Date of defense: 2021-05-19)
This thesis presents the development of different self-powered devices that allow the conductivity measurement of liquid samples, from different types of water samples to biological fluids. The devices ...
Vilaplana Saiz, Marta (Date of defense: 2021-01-22)
This thesis shows the research carried out on two specific diseases: familial hypercholesterolemia, which is included within the cardiovascular diseases group, and cancer. These diseases are the major ...
Barbieri, Maria Vittoria (Date of defense: 2021-01-28)
The assessment of pesticide occurrence in different environmental compartments has become a matter of outstanding importance since its effects on exposed organisms may be considered a warning on the ...
Recalde-Percaz, Leire (Date of defense: 2021-06-30)
Metastases are considered the last stage of tumour progression and the main cause of death associated to solid tumours. There are no effective treatments for metastasis which remain non- curable with ...
Licht, David (Date of defense: 2021-04-14)
In this thesis we present a new aspect pertaining to the effective field theory of general relativity in the limit of a large number D of dimensions. We demonstrate that the theory initially developed ...