Universitat de Barcelona
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The human capacity for language is made up of various cognitive subcomponents, the convergence of which allows our species a unique ability to relay our thoughts. Identifying these subcomponents and establishing how they ...
The role of consumer-resource relationship is the basis of the structure and functioning of ecological communities. The traditional lens for studying such interactions have tended to omit the importance of the species ...
The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor with key functions downstream of receptor tyrosine kinase (RTK)-Ras-MAPK signaling pathways. In both Drosophila and mammals, Cic is expressed as ...
Previous studies have reported the importance of carnitine palmitoyltransferase (CPT) 1A as an essential part of downstream ghrelin signaling in the central nervous system (CNS) for the control of food intake. Lipid ...
The transforming growth factor-beta (TGF-β) is a cytokine involved in many physiological and pathological processes. Its dual role has been described in the liver, where it can either induce pro- or anti-apoptotic signals. ...
[eng] The arrival of antiangiogenic therapies represented a huge advance in the treatment of different tumors, such as renal carcinoma. However, despite initial good results, some tumors were able to develop different ...
Psoriasis is a common immune-mediated inflammatory skin condition affecting around 2% of the population worldwide. Different disease subtypes have been described regarding their specific clinical phenotype: chronic plaques, ...
Many second language (L2) learners find L2 pronunciation difficult and experience perception and production problems leading to accented speech. There exists a great inter-learner variation in L2 phonological acquisition ...
Modern lifestyles in an increasing number of human societies include consuming an excess of saturated fats and refined sugars as well as enjoying microbiologically aseptic environments. Maintaining the appropriate ...
Protein homeostasis (proteostasis) results from the fine regulation of synthesis and degradation. The nuclear cofactor DOR/TP53INP2 was identified originally as a protein expressed in PML of nuclear bodies. However, in ...
Colorectal cancer (CRC) is a leading cause of death worldwide and tumour recurrence is a frequent complication that arises from minimal residual disease and shows up after a period of clinical dormancy. Slow-cycling cancer ...
Childhood obesity and overweight can often cause severe complications, including hypertension, dyslipidemia, insulin resistance, type 2 diabetes, and non-alcoholic fatty liver disease, amongst other disorders. Several ...
Obesity and associated metabolic diseases have reached epidemic proportions, affecting not only high-income countries but also low- and middle-income ones. In this context, the search for therapeutic approaches to treat ...
This Thesis has been divided into three different chapters, the regulation of Fsp27 during the fasting adaptation, the transcriptional regulation of Fsp27 in liver and finally the role of FSP27 as a lipid-droplet protein ...
In the last two decades, it has been done a thoroughly research about the role of Guanylate Cyclase Activating Proteins (GCAPs) in photoreceptor cells of the retina as activity regulators of Retinal Guanylate Cyclase ...
HDAC11 is the newest member of the histone deacetylase (HDAC) family and one of the less studied. Its expression was described to be enriched in skeletal muscle tissues from the first moment of its discovery, yet now after ...
The excessive consumption of calorie-rich foods, together with a sedentary lifestyle, drive the actual global obesity pandemic. Obesity is the leading cause of several other metabolic disorders, such as diabetes, cardiovascular ...
Within the hematopoietic system, all mature blood cells are generated. Every differentiation step is characterized by the activation of a new, lineage specific, genetic program and the extinction of the previous one. To ...
The human leukocyte antigen-G (HLA-G) is a non-classic MHC class I molecule. It is called “non-classic” because it differs from classic MHC class I molecules due to its very low amount of polymorphism and highly tissue-restricted ...
[spa] INTRODUCCIÓN: El síndrome de hiperestimulación ovárica (SHO) es la complicación yatrogénica más grave y potencialmente mortal asociada con las técnicas de reproducción asistida (TRA). El SHO moderado o grave puede ...
