Now showing items 10783-10802 of 11118

    Understanding chromosomal instability-induced senescence 

    Santos Tapia, Celia (Date of defense: 2019-10-30)

    Aneuploidy, defined as a chromosome number that deviates from a multiple of the haploid set, is a common feature in human cancer, and around 70% of human solid tumours are aneuploid. The resulting metabolic imbalance is ...

    Understanding different opportunities to prevent severe disease and reduce mortality in African infants and children: From vertical transmission prevention to enhanced diagnosis of life-threatening conditions of childhood = Oportunidades para prevenir enfermedades graves y reducir la mortalidad en lactantes y niños africanos. Prevención de la transmisión vertical y mejora del diagnóstico de enfermedades que amenazan la vida de los niños 

    Madrid Castillo, María Dolores (Date of defense: 2018-03-02)

    Infant and child mortality have played a crucial role in health transition patterns and both have been considered as good indicators of development and demographic modernization. The establishment of the Millennium Development ...

    Understanding diversification and dispersion patterns in planarians (Tricladida, Platyhelminthes): form one to hundreds of genes 

    Benítez Álvarez, Lisandra (Date of defense: 2022-06-16)

    Evolutionary Biology offers a set of methods and theories to elucidate the evolutionary processes that lead to the diversification of life. With the development of sequencing technologies, the access to genetic data has ...

    Understanding Entrepreneurial Legitimacy in the digital space: The Where, The Who and The How 

    Arroyo Carrasco, Lizbeth Elaine (Date of defense: 2022-04-25)

    The Industry 4.0 revolution is undergoing a profound transformation due to the unstoppable digitalization of our society. This historic dynamic is characterised by hyperconnectivity, where the Technosphere, the natural ...

    Understanding Innovation within the context of the Integration of Management Systems 

    Hernández Vivanco, Alfonso Antonio (Date of defense: 2018-07-16)

    In an increasingly competitive world driven by fast changes, where resources are limited and where stakeholders are more and more demanding, societies, from individuals to companies and governments, are challenged to pursue ...

    Understanding migration of pelagic seabirds with stable isotopes and geolocation 

    Neto Militao, Teresa Afonso (Date of defense: 2016-10-07)

    Animal migration is an amazing widespread phenomenon that forms an essential component of the animal life history. Animals usually migrate to take advantages of changes in resource availability in space and time or to find ...

    Understanding PI3K signalling in vessel growth and pathophysiology 

    Kobialka, Piotr (Date of defense: 2020-11-13)

    [eng] Our knowledge on the molecular basis behind physiological angiogenesis has significantly expanded in the last two decades. This progress also led to improvement in understanding of many vascular-related diseases in ...

    Understanding Recent Food Price Patterns: A Time-Series Approach 

    Hisham Abdelradi Khalaf, Fadi Mohamed (Date of defense: 2014-10-17)

    The guiding theme of this thesis is the empirical analysis of recent food price behavior. It is composed of three applied studies that address the impacts of energy prices on both food price levels and volatility, as well ...

    Understanding resilience through biodiversity: developing systemic tools for marine conservation in temperate rocky reefs 

    Sanabria Fernández, José Antonio (Date of defense: 2021-01-13)

    The degradation of natural diversity results in the erosion of key systemic properties such as resilience, or the capacity to recover from disturbances. Resilience loss leads to an increase in the fragility and vulnerability ...

    Understanding stochastic and deterministric microbial assembly processes in ephemeral saline lakes 

    Menéndez Serra, Mateu (Date of defense: 2022-06-16)

    Understanding the mechanisms and processes driving biological com- munities assembly, i.e. determining why a specific community is found under certain circumstances, is one of the fundamental questions in ecology. The ...

    Understanding the link between chromatin structure, chromosome conformation and gene regulation 

    Buitrago Ospina, Diana Camila (Date of defense: 2019-12-16)

    Understanding the connection between DNA organization in the nucleus, and cell functioning is one of the most intriguing problems in biology. Although many interdisciplinary efforts have been developed for this aim, the ...

    Understanding the measurements and variability of aerosol optical properties in NE Spain 

    Yus Díez, Jesús (Date of defense: 2022-12-20)

    [eng] Atmospheric aerosol particles are key for regulating Earth’s atmosphere processes, and are estimated to present an overall cooling effect on the Earth’s climate. Given the current climate change crisis, and the need ...

    Understanding the mechanisms of food intake and obesity in Down syndrome is supported by behavioral and neurochemical abnormalities 

    Fructuoso Castellar, Marta (Date of defense: 2017-09-18)

    Obesity prevalence is higher in Down syndrome (DS) than in the general population. Beyond metabolic alterations, individuals with DS present increased impulsivity, a trait observed in obese people and in compulsive eaters ...

    Understanding the physical origin, topology and strength of noncovalent interactions by means of computational tools 

    Velasquez Benites, Juan Diego (Date of defense: 2022-07-14)

    The structure and stability of molecules, the formation of supramolecular aggregates in the solid state or in solution and, therefore, many chemical and biological processes in which they participate depend heavily on ...

    Understanding the processes that controlled rifting of the Tyrrhenian basin 

    Guzman Vendrell, Montserrat (Date of defense: 2015-11-30)

    This thesis is focused in the processes that took place in the Tyrrhenian Sea, which is a Neogene basin belonging to the Western Mediterranean realm. Its formation is related with the subduction system of the African plate ...

    Understanding the processes that shape the genetic diversity of freshwater planarians (Platyhelminthes, Tricladida, Dugesiidae) = Estudi dels processos que modelen la diversitat genètica en les planàries d'aigua dolça (Platyhelminthes, Tricladida, Dugesiidae) 

    Leria Florensa, Laia (Date of defense: 2019-10-28)

    The main goal of the present thesis has been to shed light into the processes that shape the genetic diversity of organisms, focussing in the following factors: the type of reproduction, the morphological diversity of ...

    Understanding the role of sensor diversity and redundancy to encode for chemical information in gas sensor arrays 

    Fernández Romero, Luis (Date of defense: 2016-01-25)

    Electronic noses (e-noses) have been utilized during the past three decades as general purpose instruments for chemical sensing. These instruments are inspired by natural olfactory systems, where fine odour discrimination ...

    Understanding the transport mechanism of BBB peptide shuttles: THRre and MiniAp-4 as case studies 

    Fuster Juncà, Cristina (Date of defense: 2019-06-14)

    The research work presented in this thesis aims to understand the transport mechanism of two described BBB-shuttles, THRre and MiniAp-4. To achieve these objectives, different techniques have been used as solid phase peptide ...

    Unidades pluriverbales en los diccionarios del español de Costa Rica 

    Cordero Monge, Sergio (Date of defense: 2016-02-26)

    En esta de investigación se analiza el tratamiento lexicográfico de las locuciones verbales en tres diccionarios que registran léxico diferencial del español de Costa Rica; dos de ellos dedicados exclusivamente a esta ...

    Unified Framework for the Study of Sport-Related Behavior 

    Vázquez Justes, Pablo (Date of defense: 2017-01-24)

    A high disciplinary specialization and development of context-specific languages in sport science has promoted its current fragmentation and a lack of communication and transfer of knowledge among scientists. However, ...