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Now showing items 23005-23024 of 41845
Investigation of the influence of the membrane lipid environment on g protein-coupled receptor activation by molecular dynamics simulations
Els receptors acoblats a proteïnes G (GPCRs) són importants dianes terapèutiques per a nombroses malalties. Si bé els GPCRs s’han estudiat àmpliament en les últimes dècades, els mecanismes moleculars que determinen la seva ...
Investigation of the phospholipid peripheral region of lactose permease in model membranes
The interaction between a membrane protein and its surrounding phospholipids is thought to be crucial for the correct folding and function of the protein. This thesis is focused on the investigation of the interplay between ...
Investigation of the role and modulation of autophagy for neuroprotection and nerve regeneration using models of peripheral nerve injury
Lesiones en el nervio periférico causan una disrupción axonal que puede producir una neurodegeneración retrograda. Las neuronas axotomizadas sufren una serie de cambios fenotípicos a nivel molecular y celular, algunos de ...
Investigation of the telomere maintenance system in Cushing’s syndrome: A contribution to the phenomena of early ageing and specific morbidity
La síndrome de Cushing (SC), una malaltia minoritària per secreció excessiva de cortisol, s'associa a augment de morbi-mortalitat, inclús després del tractament, comparat amb població de referència i s'associa a processos ...
Investigation on force detection methods for optical trapping and sensing inside living cells
Optical Tweezers (OT) are a light-based non-invasive tool that has played an important role during the last decades in the field of biophotonics, together with the advances in optical microscopy techniques. Optical trapping ...
Investigations in animal models of anti-NMDAR encephalitis
[eng] BACKGROUND: Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a neuronal antibody-mediated disease that associates with prominent neuropsychiatric symptoms and predominantly affects women of childbearing ...
Investigations into the role of translations in abstract algebraic logic
This memoir is divided into two parts, devoted to two topics in (ab-stract) algebraic logic. In the first part we develop a hierarchy in which propositional logics “L” are classified according to the definability conditions ...
Investigations of topological phases for quasi-1D systems
For a long time, quantum states of matter have been successfully characterized by the Ginzburg-Landau formalism that was able to classify all different types of phase transitions. This view changed with the discovery of ...
Investment, perception of risk and financial constraints
This thesis studies how firms’ investment and credit are affected by different financial imperfections related to firm and bank learning, relationship lending and financial wealth. After reviewing in chapter 2 the related ...
Invierno, primavera y otoño del Carlismo (1939 - 1976)
Aquesta tesi la portava reflexionant el seu autor des de feia força temps; és una visió del Carlisme com a col·lectiu polític, des de la Guerra Civil fins a 1976, a través de tot el Règim franquista i els inicis d’una ...
La invisibilidad de la mujer en las campañas publicitarias de prevención del VIH
Introducció: Quan es parla del VIH, queda implícita la creença que el seu contagi és per transmissió sexual i que es majoritàriament en homes gai, bisexuals i altres HSH. Les estratègies de prevenció han anat encaminades ...
Invisible structures = Estructures invisibles
This thesis is an investigation into the visualization of cosmological propositions associated with string theory. Research into the work of contemporary theoretical physics led to the question, how does one visualize what ...
Invoice factoring through blockchain technology
(English) Invoice factoring has been a popular way to provide cash flow for businesses. The primary function of a factoring system is to prevent an invoice from being factored twice. In order to prevent double factoring, ...
Involvement of adenosinergic and dopaminergic systems in the regulation of alcohol or sucrose intake: studies in rodent models of self-administration
Caffeine is a methylxanthine that acts as a nonselective adenosine antagonist, binding to adenosine A1 and A2A receptor subtypes. This substance is highly present in different beverages like coffee, tea and in energy drinks. ...
Involvement of aerial organs on the ABA accumulation in roots of Citrus plants under water deficit
La sequía es una de las situaciones más perjudiciales para el crecimiento y la supervivencia de las plantas. Sin embargo, las plantas han desarrollado estrategias para afrontar dichas condiciones, incluyendo el rápido ...
Involvement of Alternative Splicing Regulation in Adipose Tissue Thermogenic Induction
[emg] Alternative splicing (AS) is a gene expression regulatory mechanism that enables generation of multiple mRNA isoforms from a single gene which commonly are translated into proteins. This mechanism is tightly regulated ...
Involvement of dopamine in the regulation of dysfunctions related to depression in rodent models: motivational versus emotional symptoms
Depression is characterized by motivational symptoms such as anergia, fatigue and psychomotor slowing. These are highly resistant to treatment and often remain as residual symptoms after antidepressant drug therapy. It has ...
Involvement of Foxp2 in the alterations of the basal ganglia circuitry in Huntington’s Disease
Huntington’s Disease (HD) is an autosomal dominant inherited neurodegenerative disorder characterized by motor, psychiatric, and cognitive manifestations. The disease is caused by an unstable expansion of the CAG trinucleotide ...
Involvement of photoinhibition and redox balance in acclimation and developmental processes of plants
Environmental constraints and developmental processes in plants can lead to light energy excess in chloroplasts by lowering the threshold at which light becomes saturating by a lack of electron acceptors in the light-processing ...
