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Mostrando ítems 10093-10112 de 41723
Development of model-driven approaches for metabolic flux analysis and anticancer drug discovery
Metabolism is a hallmark of life and underlies most biological processes in both health and disease. For instance, dysregulation of liver metabolism underlies multifactorial disorders such as diabetes or obesity. Similarly, ...
Development of models to evaluate the potential of building roofs to reduce air pollution: application to the case of Tehran
(English) Environmental protection is a principle of both Millennium Development Goals and sustainable development, underscoring critical issues like greenhouse gases, global warming, and air pollution. Air pollution is a ...
Development of molecular lateral flow biosensors for non-covered medical needs
La pandèmia actual de SARS-CoV-2 ha ressaltat la importància de poder desenvolupar, produir i desplegar ràpidament proves de diagnòstic per a malalties infeccioses emergents, ja que el SARS-CoV-2 no serà l'última amenaça. ...
Development of molecular monitoring methods and assessment of the environmental fate of the biological control agent of fire blight Pseudomonas fluorescens EPS62e
Pseudomonas fluorescens EPS62e es va seleccionar com a agent de biocontrol del foc bacterià per la seva eficàcia en el control de Erwinia amylovora. En aquest treball es van desenvolupar mètodes de traçabilitat que van ...
Development of molecular-based techniques for the detection, identification and quantification of food-borne pathogens
La presencia de microorganismos patógenos en alimentos es uno de los problemas esenciales en salud pública, y las enfermedades producidas por los mismos es una de las causas más importantes de enfermedad. Por tanto, la ...
Development of mono and multilayer membranes of polypropylene and ethylene-propylene copolymers via cast film extrusion and stretching
This dissertation investigates the three-stage method MEAUS (melt-extrusion, annealing, and uniaxial stretching) for producing microporous membranes. This method for membrane preparation is a solvent-free process based on ...
Development of mucus permeating nanoparticles-based drug delivery systems
Existeix un interès creixent, tant en el món acadèmic com en la recerca industrial en el desenvolupament de sistemes d’alliberament de fàrmacs macromoleculars (proteïnes, pèptids, oligonucleotids) capaços de travessar la ...
Development of multifunctional biopolymeric materials for teatment of decubitus ulcers
Chronic wounds including pressure, venous, arterial and diabetic neuropathic ulcers, represent a significant burden to the healthcare system. These different chronic wound types do not share origin or cause, however they ...
Development of multifunctional polymeric nanoparticles by nano-emulsion templating as advanced nanocarriers targeting the blood-brain barrier
Multifunctional polymeric nanoparticles (NP) represent a promising alternative for the treatment of neurodegenerative diseases using the intravenous route (i.v.). In current treatments, the effects of the intravenously ...
Development of nanofluidst based on nanoencapsulated phase change materials
The present thesis deals with the synthesis and characterisation of nanofluids including phase change materials as the nanoparticles. The main aim of the work is to develop new materials that suppose an improvement on the ...
Development of nanomaterials for environmental monitoring
El monitoreig ambiental basat en sistemes de biosensors té molta rellevància, no només en el camp de la investigació sinó també en aplicacions reals a nivell industrial. Això és degut als avantatges d’aquestes plataformes ...
Development of Nanoporous Anodic Alumina Technologies for Drug Delivery
L'alliberament de fàrmacs és un procediment en què un compost o un dispositiu allibera una molècula de manera controlada. D’aquesta manera, el medicament podrà ser sotmès a absorció, distribució, metabolisme i excreció. ...
Development of nanovectors for the targeted drug delivery of antimalarials
Malaria is arguably one of the main medical concerns worldwide because of the numbers of people affected, the severity of the disease, and the complexity of the life cycle of its causative agent, the protozoan Plasmodium ...
Development of new algorithms for depth of anesthesia monitoring integrating cerebral blood flow estimations
Cerebral blood flow (CBF) reflects the rate of delivery of arterial blood to the brain. Since no nutrients, oxygen or water can be stored in the cranial cavity due to space and pressure restrictions, a continuous perfusion ...
Development of new analytical methods using Near Infrared and Chemometrics for pharmaceutical quality control: Enhancement of modelling strategies towards a better product understanding
Obtener una alta calidad en la industria farmacéutica es un reto constante que requiere un estricto control y supervisión de los productos manufacturados. La tecnología analítica de procesos (PAT, Process Analytical ...
Development of new antimicrobial peptides and peptidomimetics and mechanism of resistance to peptide antibiotics
Nowadays in the world there is a very big problem associated with two factors related to each other. The first factor is the increase in the resistant of certain bacteria, especially the bacteria from the ESKPAE group. The ...
Development of new computational methods for fluid-structure interaction analysis of multi-fractured media
The objective of this thesis is the derivation and implementation of a robust Finite Element formulation for the solution of solid-pore fluid coupled problems in multi-fractured porous media. A coupled displacement-pore ...
Development of New Fluorophore-Tethered ortho-Carborane Systems: An Approach for Unique Photophysics and Applications
El treball que es presenta en aquest manuscrit segueix línies de recerca iniciades al Grup de Catàlisi i Síntesi Inorgànica (LMI) de l’Institut de Ciències de Materials de Barcelona (ICMAB-CSIC), basades en la síntesi, ...
Development of new GPR methodologies for soil and cement concrete pavement assessment
The study of surface geology by means of Ground Penetrating Radar (GPR) can provide information about abrupt lateral changes in the terrain. The location ofthese changes is very useful in seismic nanozonation studies, since ...
Development of New Hybrid Materials Based on Graphene Functionalised with Molecular Complexes. Evaluation of Properties and Catalytic Applications
En la presente tesis doctoral se ha descrito la síntesis de nuevos materiales híbridos basados en complejos organometálicos anclados mediante interacciones no covalentes sobre materiales derivados del grafeno. Los nuevos ...
