Browsing by Title

Development of devices and techniques for electroporation and electrical impedance spectroscopy analysis of adherent cells

García Sánchez, Tomás (Date of defense: 2015-04-24)

The present PhD dissertation is focused on the design and implementation of a microelectrode system capable of performing electroporation and electrical impedance measurements to adherent cell monolayers cultured in standard ...

Development of devices to integrate in automatic methodologies for determining radionuclides in residues and environmental samples

Rodas Ceballos, Melisa Alejandra (Date of defense: 2018-12-10)

[eng] In this thesis, different devices have been developed, using 3D printing technology or numerical control tools, which have been integrated into automatic analysis systems that use flow injection analysis techniques. The ...

Development of diagnostic platform for detection of biological agents and toxic microalgae using isothermal amplification

Mayboroda, Olena (Date of defense: 2017-11-17)

L'objectiu principal d’aquesta tesis és desenvolupar sensors d’ADN portàtils i fàcils d’utilitzar per analitzar material genètic al lloc on sigui necessari, superant les limitacions de les tecnologies actuals. Per dur-ho ...

Development of diffuse large B-celllymphoma mouse models and role of CXCR4 in dissemination = Desarrollo de modelos murinos de linfoma difuso de células grandes B y papel de CXCR4 en diseminación

Moreno Jiménez, María José (Date of defense: 2014-06-10)

Diffuse large B-cell lymphoma (DLBCL) is a clinically and genetically heterogeneous disease, accounting for 30% of all non-Hodgkin lymphoma cases. Although the addition of rituximab to standard treatment (CHOP: cyclophosphamide, ...

Development of displacement electrochemical inmunosensors: the case of 2,4,6-trichloroanisole

Duarte, Maria Viviana (Date of defense: 2007-12-12)

Development of displacement El objetivo de este trabajo es explorar y explotar los principios de funcionamiento de un Inmunosensor Electroquímico de Desplazamiento [(Displacement Electrochemical Immunosensor (DEI)] y también ...

Development of DNA Detection Bioassays Based on DNA Binding Proteins

Ruhela, Ankur (Date of defense: 2023-11-24)

Les proteïnes d'unió a l'ADN (PUA) són components essencials de molts processos biològics. La seva capacitat de reconèixer i unir-se estretament a l'ADN d'una manera específica o no específica de la seqüència, els converteix ...

Development of DNA methylation biomarkers to study epigenetic inheritance and integration of environmental stimuli

Sánchez Baizán, Núria (Date of defense: 2023-10-27)

[eng] Epigenetic mechanisms play a vital role in gene expression regulation and phenotype determination. This thesis aimed to comprehensively investigate the transcriptome, the methylome and the influence of intrinsic (such ...

Development of doubled haploids, chromosome doubling and CRISPR/Cas9 techniques in melon for the next generation of breeding

Hooghvorst, Isidre (Date of defense: 2021-04-28)

The general aim of this PhD thesis was to study, develop and apply different breeding techniques in melon species in order to produce new commercial cultivars. The three specific objectives of this thesis are: 1. To ...

Development of dynamic textiles based on shape memory polyurethane (SMPU) for applications in car seat upholstery

González Bertran, Judit (Date of defense: 2023-10-25)

(English) In recent years, numerous studies have been carried out on functional textiles due to their ability to adapt and interact with the environment. In particular, special focus has been placed on dynamic textiles ...

Development of efficient eukaryotic and bacterial expression systems for functional studies of recombinant proteins of biomedical interest

Mariño Puertas, Laura (Date of defense: 2020-02-14)

Al llarg aquesta tesi s’han fet molts esforços per desenvolupar un sistema d’expressió heteròloga de glicoproteïnes humanes d’alt rendiment, puresa i homogeneïtat, així amb la flexibilitat necessària per modificar la ...

Development of efficient numerical models for the simulation of low velocity impact and compression after impact on composite structures

Soto Masip, Albert (Date of defense: 2018-09-07)

Fiber reinforced composite materials are nowadays used in several industrial applications that pursue structural weight reduction to reduce fuel consumption. The stiffness-to-weight and strength-to-weight ratios of composite ...

Development of efficient testing methods and cohesive zone models for analyzing fatigue-driven delamination in 3D laminated composite structures

Carreras Blasco, Laura (Date of defense: 2019-07-17)

The overall purpose of this Ph.D. thesis is to contribute to the reliable design of composite structures subjected to fatigue-driven delamination. The aim is motivated by a wish to reduce the amount of experimental testing ...

Development of electrochemical (bio)sensors and microanalytical systems. Application to the wine industry

Giménez Gómez, Pablo (Date of defense: 2017-06-28)

El mercado creciente de la industria del vino necesita garantizar los estándares de calidad y la protección del consumidor mediante el seguimiento de varios parámetros a lo largo del proceso de elaboración del vino. La ...

Development of electrochemical biosensors and solid-phase amplification methods for the detection of human papillomavirus genes

Civit Pitarch, Laia (Date of defense: 2012-05-03)

Un diagnòstic ràpid, precís i fiable és crucial per a la identificació d'una malaltia, com el càncer, on la detecció precoç pot millorar els resultants del tractament. El càncer de coll uterí és el tercer més comunament ...