2024-03-29T05:22:23Zhttps://www.tdx.cat/oai/requestoai:www.tdx.cat:10803/530622024-03-15T10:57:33Zcom_10803_236col_10803_690278
nam a 5i 4500
DDT
Pyrethroids
Indoor Residual Spraying
Malaria Vector Control
Thatch
Umbilical cord
Mozambique
Pulveritzaciò Residual Intradomiciliaria
Control del Vector de la Malària
Llet Materna
Exposure to organochlorine compounds at the aerly stages of DDT use for indoor residual spraying in domestic environments in Manhiça, Mozambique.
[Barcelona] :
Universitat Pompeu Fabra,
2012
Accés lliure
http://hdl.handle.net/10803/53062
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Manaca, Maria Nélia Joquim,
autor
Programa de doctorat en Biomedicina,
degree
1 recurs en línia (171 pàgines)
Tesi
Doctorat
Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut
2011
Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut
Tesis i dissertacions electròniques
Grimalt Obrador, Joan,
supervisor acadèmic
Dobaño, Carlota,
supervisor acadèmic
TDX
Past and present uses of DDT and pyrethroids have led to their incorporation into humans, mainly through the food chain and sometimes by direct exposure.
The present work focuses on establishing the levels of DDT, its analogous compounds (DDE and DDD), and pyrethroids in humans and the human environment in Manhiça, a rural area where they have been used as insecticides for indoor residual spraying (IRS) and insecticide treated nets (ITN) in malaria control programs. Thatch samples from human dwellings, breast milk from pregnant women and cord blood from newborns were analyzed for assessment of the concentration levels of these compounds.
The results showed that DDT and its analogues were already present in humans and dwellings before reintroduction of this insecticide for IRS. As consequence of these applications DDT concentrations increased significantly. The higher proportion of 4,4’-DDT than 4,4’-DDE evidenced that the observed amounts were due to recent applications of this insecticide. Concerning pyrethroids, their presence has been identified in both breast milk and human dwellings showing that both agricultural applications and use for ITN may be responsible for their occurrence in humans and human environments of Manhiça.
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