2024-03-28T17:00:51Zhttps://www.tdx.cat/oai/requestoai:www.tdx.cat:10803/3141752017-09-19T05:01:55Zcom_10803_284col_10803_287
nam a 5i 4500
Sobrediagnòstic
Cribratge
Cancer
Sobrediagnostico
Cribado
Vitamina D
Overdiagnosis
Screening
Quality of life
Palliative
Cancer and quality of life. Breast cancer overdiagnosis and design of an intervention to improve the quality of life of oncological patients in palliative care
[Lleida] :
Universitat de Lleida,
2015
Accés lliure
http://hdl.handle.net/10803/314175
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Martínez Alonso, Montserrat,
autor
1 recurs en línia (106 pàgines)
Tesi
Doctorat
Universitat de Lleida. Departament de Ciències Mèdiques Bàsiques
2015
Universitat de Lleida. Departament de Ciències Mèdiques Bàsiques
Tesis i dissertacions electròniques
Rué i Monné, Montserrat,
supervisor acadèmic
Dusso Rosso, Adriana,
supervisor acadèmic
TDX
Early detection of breast cancer (BC) with mammography may cause overdiagnosis and
overtreatment. In the other extreme, for advanced cancer patients in palliative care quality of life
is the most important outcome. Our aims are: to model invasive BC incidence trends in Catalonia
and quantify the extent of BC overdiagnosis; to perform a systematic review of all the clinical
outcomes reported in cancer after the supplementation with vitamin D (VD); to assess serum VD
deficiency and its relationship with quality of life, fatigue, and physical and functional
performance; and to design a randomized controlled trial (VIDAFACT) to assess VD
effectiveness in increasing quality of life. Our estimates support the existence of overdiagnosis in
Catalonia attributable to mammography usage. The results from both the cross-sectional study
and the systematic review, support the need for VIDAFACT to provide data about VD
supplementation effectiveness on improving overall quality of life.
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