2024-03-28T21:46:15Zhttps://www.tdx.cat/oai/requestoai:www.tdx.cat:10803/6691152020-06-05T12:11:38Zcom_10803_480col_10803_386426
00925njm 22002777a 4500
dc
Moles Tena, Pamela
author
2011-07-28
In the present PhD thesis, we report a complete theoretical study that thoroughly investigates several aspects of a complex biological system: the action of artemisinin and its derivatives against malaria. This study, conducted in the field of Theoretical and Computational Chemistry, is of great interest because it allows to uncover many aspects of the reaction mechanism of these drugs, so far, not known or controversial. The results obtained nicely agree with the experimental data known to date, and hence it can be assessed that our work has given a sound explanation of the observed facts relative to the anti-malarial mode of action of artemisinin and its derivatives.
http://hdl.handle.net/10803/669115
malaria
artemisinina
estudio teórico
Estudio teórico del mecanismo antimalaria de la artemisinina y sus derivados