Now showing items 173-182 of 182

    The contribution of LMO4 to neural development: generatin neuronal subtypes in the dorsal spinal cord and controlling EMT in neural crest cells and Neuroblastoma = La contribución de LMO4 al desarrollo neural: la generación de subtipos neuronales de la médula dorsal espinal y el control de la EMT en las células de la cresta neural y de Neuroblastoma 

    Ferronha, Tiago Guimaràes (Date of defense: 2013-07-16)

    The formation of the central nervous system (CNS) requires the generation of a remarkable diversity of neurons, which must be produced in adequate amounts in the location and timing during development. Studies on the ...

    The evolution of bilaterian body-plan: perspectives from the developmental genetics of the Acoela (Aeoelomorpha). 

    Chiodin, Marta (Date of defense: 2013-02-15)

    The mesoderm is the third germ layer, which is formed at gastrulation between the endoderm and the ectoderm in triploblastsc animals (Bilateria). The mesoderm differentiates into muscles, connective tissues and coelomic ...

    The Identification and the Functional Validation of Eye Development and Regeneration Genes in Schmidtea Mediterranea 

    Calvo Lozano, Beatriz (Date of defense: 2015-10-23)

    Discovering the master genes necessary to build the eye in an invertebrate model such as S. mediterranea could help us to understand numerous retinopathies and age-related degeneration of the human eye. The aim of this ...

    Towards High Quality Single-cell Experiments: Approaches, Applications and Performance 

    Lafzi, Atefeh (Date of defense: 2020-05-29)

    Single-cell RNA sequencing has revolutionized the way molecular mechanisms were being studied by allowing the dissection of gene expression at single-cell resolution. The data acquired from scRNA-seq provides great ...

    Transcriptoma d'ash2: dianes i funció, El 

    Beltran Agulló, Sergi (Date of defense: 2006-07-21)

    El gen <i>absent, small, or homeotic discs 2 (ash2)</i> és un membre del grup dels trithorax (trxG), reguladors positius de la transcripció dels gens homeòtics. Els al·lels mutants per ash2 són letals larvals o pupals i ...

    Transcriptomics and identification of candidate genes for studies in Coleoptera 

    Vizán-Rico, Helena Isabel (Date of defense: 2022-01-28)

    The molecular evolution of genes, joined to the differences between sexes, is a matter of interest poorly investigated across the class Insecta from a global perspective. The abundance of insect species, the high diversity ...

    The Transposon Bari-Jheh in Drosophila melanogaster: adaptive phenotypes, molecular mechanisms, and genetic inheritance = El transposón Bari-Jheh en Drosophila melanogaster: fenotipos adaptativos, mecanismos moleculares y herencia genética 

    Guio Leiman, Laín (Date of defense: 2016-03-17)

    Elucidating the fitness effects of natural genetic variants is one of the current major challenges in evolutionary biology. Understanding the interplay between genotype, phenotype and environment is necessary to make ...

    Unravelling the Role of Long Noncoding RNAs in the Context of Cell-growth and Regeneration 

    Amador Rios, Raziel (Date of defense: 2022-02-10)

    Long noncoding RNAs (lncRNAs) have proven biological roles in plethora cellular contexts. Nonetheless, only a handful have been clearly characterized, leaving thousands of newly discovered lncRNAs without an associated ...

    Variabilitat de la mongeta Ganxet ("Phaseolus vulgaris" L.): determinació de tipologies i selecció de línies comercials 

    Sánchez Bell, Esther (Date of defense: 2004-01-27)

    En el context europeu actual l'ampliació en l'oferta de cultius i tipus varietals és una eina important per a l'agricultor. Les varietats tradicionals bé poden ocupar un lloc significatiu dins del panorama agrícola actual ...

    Variants del gen APC i càncer colorectal. 

    Menéndez Vilà, Mireia (Date of defense: 2007-07-18)

    Les mutacions germinals d'elevada penetrància del gen APC que originen una proteïna truncada són les responsables de la majoria de casos de poliposi, mentre que les variants missense, que canvien un aminoàcid de la proteïna, ...