Universitat de Barcelona
Now showing items 101-116 of 116
Conservation actions aim to preserve and recover animal and plant species using in-situ or ex- situ strategies. The first, aims to protect and sustain populations in their natural habitat, the second are implemented when ...
Most human solid tumors present signs of genomic instability. Activated oncogenes have been proposed to induce genomic instability through the generation of replicative stress. In this thesis, we have sown that the expression ...
L’objectiu principal de la present tesi doctoral ha estat l’optimització i aplicació de procediments basats en la seqüenciació massiva per a la descripció del viroma associat a l’aigua residual i a altres mostres d’interès ...
El virus de l’hepatitis A (HAV), el prototip del gènere Hepatovirus, té una sèrie de característiques que el diferencien de la resta de membres de la família Picornaviridae. Entre aquestes, la via de sortida descrita ...
This thesis is the product of three and a half years working on the complex world of metabolomics and nutrition. All the work presented here is focussed on the problems arising from associating and integrating ...
Neuroblastoma (NB) is the most common extracraneal solid tumor diagnosed in the first 5 years of childhood and accounts for approximately 15% of all pediatric cancer-related deaths. At the time of diagnosis, about half of ...
[eng] MECP2 is a multifunctional gene involved in multiple processes such as transcription regulation, chromatin remodelling, splicing and miRNA regulation. Malfunction of MECP2 due to loss of function mutations leads to ...
The translation of Next Generation Sequencing (NGS) technologies from the research field to the clinical setting and, specifically, the results obtained in terms of diagnostic yield remain far from expected. This situation ...
La sumoïlació és una modificació posttraduccional (PTM) que consisteix en la conjugació covalent i reversible d’una proteïna SUMO (Small ubiquitin-like modifier) al residu lisina d’una proteïna diana. Igual que la ubiquitina, ...
Colorectal cancer (CRC) is the second-highest cause for cancer-related mortality worldwide. Patients suffering from CRC generally don’t die from primary tumours but rather from metastasis, for which there are no effective ...
La presente tesis titulada Técnicas moleculares para la caracterización microbiológica de los procesos de eliminación de nutrientes en las EDARs, se ha desarrollado desde dos puntos de vista, el primero fue la puesta a ...
Uno de los mecanismos genéticos que facilitan la innovación evolutiva es la formación de nuevos genes. De entre los procesos que permiten generar nuevos genes, la domesticación molecular de genes transposónicos es uno de ...
Evolutionary Biology offers a set of methods and theories to elucidate the evolutionary processes that lead to the diversification of life. With the development of sequencing technologies, the access to genetic data has ...
The main goal of the present thesis has been to shed light into the processes that shape the genetic diversity of organisms, focussing in the following factors: the type of reproduction, the morphological diversity of ...
La presente investigación explora la utilidad de los bacteriófagos y otros microorganismos indicadores de la contaminación fecal en relación a dos grandes tipos de sólidos relevantes en el ciclo del agua, los lodos de ...
The retina consists of several structured layers of highly specialized neurons that capture and process light stimuli enabling vision. Such a fine architecture turns retinal differentiation into an extremely complex event ...
