Now showing items 15-34 of 116
Parra Acero, Helena (Date of defense: 2019-02-08)
Animal multicellular structure depends on three general mechanisms: cell adhesion, cell communication and cell differentiation. Some of these mechanisms were thought to be specific to animals. Genome sequencing of unicellular ...
Sureda Gómez, Miquel (Date of defense: 2017-09-15)
La vía Wnt canónica es una vía de señalización muy conservada a lo largo de la evolución de los animales. Esta vía controla múltiples procesos como es la especificación del eje anteroposterior o el destino celular durante ...
Vu Cantero, Diem-Lan (Date of defense: 2020-01-20)
Novel human astrovirus (HAstV) are enteric virus belonging to the Astroviridae family and were discovered 10 years ago by high-throughput sequencing. They are divided in two different clades, the HAstV-MLB including 3 ...
Potrony Mateu, Míriam (Date of defense: 2018-09-28)
Melanoma is the malignant tumor arising from melanocytes and is the most aggressive of the common skin cancers. Melanoma is the tumor with the highest heritability (58%) and around 10% of cases occur in a familial context. ...
De Giorgio, Ettore (Date of defense: 2022-03-18)
Chitin has a recognised importance in physiology but also as a biomaterial. In insects, it is the principal component of the apical extracellular matrix of epidermis, tracheae, foregut and hindgut. In these compartments, ...
Castilla-Vallmanya, Laura (Date of defense: 2021-11-04)
Neurodevelopmental disorders (NDDs) are a group of chronic diseases in which the development of the central nervous system is impaired, resulting in disability at the neuropsychiatric, motor and/or intellectual level. Some ...
Herrera Úbeda, Carlos (Date of defense: 2019-12-16)
In this thesis we have covered the importance of finding underlying conservation events to better understand the regulatory mechanisms of important development orchestrators like the Hox cluster. As an example of these ...
Puigvert Sànchez, Marina (Date of defense: 2018-06-05)
The plant pathogen Ralstonia solanacearum is the causal agent of bacterial wilt, a highly aggressive disease responsible for important worldwide economic losses. Many virulence factors in R. solanacearum have been already ...
El Mouali Benomar, Youssef (Date of defense: 2017-09-15)
The regulation of the expression of virulence genes in Salmonella enterica serovar Typhimurium is an intensively studied feature of Salmonella lifestyle. How Salmonella integrates environmental signals to activate ...
Guerrero Ludueña, Richard E. (Date of defense: 2017-09-07)
Healthcare is changing, and the era of data-driven healthcare organisations is increasingly popular. Data-Driven approaches (e.g., Machine Learning, Metaheuristics, Modelling and Simulation, Data Analytics, and Data ...
Ferrández Roldán, Alfonso (Date of defense: 2021-02-22)
The bloom of genomic data has revealed a vast amount of gene losses across all life kingdoms. However, the impact of gene loss on the evolution of the mechanisms of embryo development remains an important challenge. In ...
Chavarria Miró, Gemma (Date of defense: 2023-10-30)
[cat] El virus de l'hepatitis A (HAV) s'allibera de cèl·lules infectades principalment embolcallat en membranes de la pròpia cèl·lula, formant partícules quasi embolcallades (eHAV). Es creu que la biogènesis d’eHAV podria ...
Toribio Avedillo, Daniel (Date of defense: 2021-07-23)
El control de la transmisión de patógenos víricos a través de la ruta fecal-oral ha adquirido recientemente relevancia e interés público. Para mantener este control, es necesario determinar indicadores apropiados para la ...
Frías López, Cristina (Date of defense: 2019-11-29)
Las tecnologías de secuenciación de próxima generación (NGS) proporcionan datos potentes para investigar cuestiones biológicas y evolutivas fundamentales, como estudios relacionados con la genómica evolutiva de la adaptación ...
Sánchez Herrero, José Francisco (Date of defense: 2019-12-13)
Encontramos una gran cantidad de información genómica en bases de datos para numerosos organismos pero existe un sesgo hacia ciertos grupos taxonómicos por el interés económico, social o sanitario. Los avances y el ...
Bruguera Casamada, Carmina (Date of defense: 2018-11-09)
Els mètodes electroquímics s’estan estudiant com a mètodes alternatius pel tractament de l’aigua amb la finalitat d’eliminar-ne els contaminants, tant els microbiològics com els químics, en qualsevol punt del cicle de ...
Blanco Ortiz, Albert (Date of defense: 2021-09-07)
Besides classic enteric viruses such hepatitis A virus and norovirus, there are other viruses that can reach water sources without being part of their transmission route. Some of these pathogens are enveloped viruses, which ...
Cárdenas Youngs, Yexenia I. (Date of defense: 2018-06-20)
Esta tesis doctoral tuvo como objetivo principal identificar y cuantificar la presencia de bacterias patógenas, mediante el uso de indicadores de contaminación fecal y Legionella en aguas de riego aplicando métodos ...
Castillo Andreo, David (Date of defense: 2023-03-01)
[eng] Microscopy and Chromosome Conformation Capture (3C) are the two main techniques for studying the three-dimensional (3D) organization of the genome. Microscopy, allowing the visualization of genomic loci in individual ...
Camilleri Robles, Carlos (Date of defense: 2022-07-22)
Long non-coding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides that lack protein-coding potential. Although multiple examples of functional lncRNAs have been described, particularly regulating gene ...