Browsing Facultat de Farmàcia i Ciències de l'Alimentació by Subject "616.3"

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Data integration in inflammatory bowel disease

Revilla Sancho, Lluís (Date of defense: 2022-06-14)

INTRODUCTION: Inflammatory bowel disease is a complex intestinal disease with several genetic and environmental factors that can influence its course. The ethiology and pathophysiology of the disease is not fully understood. ...

Dissecting the cellular basis of Inflammatory Bowel Disease through Single-cell RNA sequencing

Garrido Trigo, Alba (Date of defense: 2023-05-19)

[eng] Crohn’s disease and ulcerative colitis are chronic inflammatory bowel diseases that show perplexing heterogeneity which is poorly understood at a cellular level. We applied single-cell RNA sequencing and CosMxTM ...

Human Primary Organoid-Derived Epithelial Monolayers as a Novel Strategy for the Study of Adherent Invasive Escherichia coli pathogenicity and the effects of Postbiotics on Intestinal Epithelial Function

Mayorgas, Aida (Date of defense: 2021-09-08)

Inflammatory bowel disorders – such as Inflammatory Bowel Disease (IBD) – are rising worldwide. A well-known feature of IBD is dysbiosis of the gut microbiota, characterized by a significant reduction of beneficial strains ...

Structural studies on Porphyromonas gingivalis proteins

Schmitz, Claus-A. (Date of defense: 2023-04-26)

[eng] We investigated the structure function relationship of PorX by combined biophysical experiments and enzymatic assays. As a regulator of the type 9 secretion system (T9SS) of the human pathogen Porphyromonas gingivalis ...