Universitat de Barcelona
Now showing items 185-204 of 304
[spa] De entre las vacunas de ácidos nucleicos, las basadas en ARNm autoreplicativos (replicones) o ARNm convencionales unidos a diferentes nanopartículas (NPs) como: oro (Au-NP), nanocápsulas (NCs), ácido poliláctico ...
The incidence of neurodegenerative diseases, such as Alzheimer's disease, increases every year due to population aging. Therefore, the development of new therapeutic strategies, such as biodegradable nanostructured systems ...
The skin is major organ of the human body, and its function is to protect the internal tissue from environmental changes, maintains the body temperature and avoid penetration of contaminants. Therefore, the skin barrier ...
Despite the latest advances in early diagnosis and increased resources employed to develop new therapeutic options, effective control of cancer disease remains a challenge. In fact, cancer is the second leading cause of ...
Neuroblastoma (NB) is a devastating paediatric cancer that originates in the developing sympathetic nervous system. These tumours account for 40% of the cases of cancer diagnosed during the first year of life and 8% of the ...
Bacterial infections are a major health concern worldwide due to the mortality and comorbidity associated levels. Besides the development of drug-resistance mechanisms, most recalcitrant infections are caused by bacteria ...
Linum album is an herbaceous plant with medical interest due to its content of podophyllotoxin (PTOX), an aryltetralin lignan with cytotoxic activity. The study of biotechnological alternatives has generated big interest. ...
The central topic of this thesis has been the study, development and validation of diverse multiplexed diagnostics platforms and techniques that can be applied to a wide range of topics, from environmental monitoring to ...
Receptor activator of nuclear factor kappa-β ligand (RANKL) and its receptor RANK are key mediators of bone resorption1,2. RANKL, its receptor RANK and its natural decoy receptor OPG, which is a competitive inhibitor that ...
[eng] The present dissertation aims at broadening current knowledge regarding the importance of bodily or tissue status of bioactive compounds that are highly abundant in the Mediterranean diet (carotenoids and polyphenols) ...
The thesis is presented as a compendium of publications and includes six different sections: General Introduction, Objectives, Results, General Discussion, Conclusions and References. The General Introduction summarizes ...
La tuberculosi és una infecció bacteriana causada per un micobacteri anomenat Mycobacterium tuberculosis. Actualment és la primera causa mundial de mortalitat causada per un agent infecciós fins i tot per sobre de la ...
Local invasion is a key cell-biological event in the metastatic cascade. In response to a changing microenvironment, cancer cells may act using two main strategies of invasion: single cell invasion and collective invasion. ...
Quatsomes are lipid-based nanovesicles developed by Nanomol group, composed of ionic surfactants and sterol derivatives. Regarding their properties, Quatsomes have shown to be highly homogenous and stable for years, important ...
Avui en dia, la única solució per a pacients que es troben en una situació de fase terminal de malaltia hepàtica o en una lesió hepàtica aguda es el transplantament. La demanda d’òrgans per a aquesta finalitat supera ...
Las lesiones del músculo esquelético son las lesiones más comunes en el ámbito deportivo (su frecuencia puede variar del 10-55%), siendo una preocupación importante en la medicina deportiva. Más del 90% de todas las lesiones ...
The use of imaging techniques routinely used for diagnosis and the assessment for treatment response in oncology allow us to analyze the changes in body composition that occur during treatment and how these changes impact ...
[eng] Myotonic dystrophy type 1 (DM1), one of the more complex diseases already known, is the most common and multisystemic rare neuromuscular disease among adults, without cure and limited pharmacological treatments. In ...
Three-dimensional ligand-based virtual screening methods have been used for many years in drug discovery, with a variable success depending on different factors, such as the complexity of the target system or the suitability ...
Oncolytic virus (OV)-based therapies have an emerging role in the treatment of solid tumors, involving both direct cell lysis and immunogenic cell death. Nonetheless, tumor- associated stroma limits the efficacy of oncolytic ...
